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The NRG Oncology Podcast

NRG Oncology
Clinical Trials
NRG Oncology
Chemotherapy
National Cancer Institute
Immunotherapy
Radiation Therapy
Radiation Oncology
Breast Cancer
Proton Therapy
Carboplatin
Paclitaxel
Hepatocellular Carcinoma
Rtog-Gog 0724
Pancreatic Cancer
Lung Cancer
Endometrial Cancer
Photon Therapy
Pembrolizumab
Cervical Cancer
Triple Negative Breast Cancer

The NRG Oncology Podcast, developed by NRG Oncology, is hosted by Drs. Stephen Chun and Lauren Henke. Stephen and Lauren delve into a variety of topics impacting the oncology community via interviews with various stakeholders throughout the NRG Oncology organization.

PublishesTwice monthlyEpisodes54Founded2 years ago
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MedicineHealth & Fitness

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Artwork for The NRG Oncology Podcast

Latest Episodes

For Breast Cancer Awareness Month, we discuss the results of the NRG-BR002 in newly oligometastatic breast cancer published in the Journal of Clinical Oncology today.

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We discuss the reported results of the NRG-HN009 p16-negative cohort presented at the ASTRO Annual Meeting Late-Breaking Abstract Session.

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We discuss the NRG-GI003 results presented during the 2026 ASTRO Annual Meeting Plenary Session.

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We discuss both the NRG-CC009 study results presented during the 2026 ASTRO Annual Meeting Plenary Session and the MAVERICK study results presented during the Clinical Trials Session.

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Recent Guests

Stephen Chimera
Radiation oncologist and principal investigator associated with BR002
NRG Oncology / University of Chicago / MD Anderson
Episode: NRG-BR002 Published in JCO
Paul Harari
Clinical oncologist, head and neck cancer expert
University of Texas MD Anderson? (as introduced in episode)
Episode: NRG-HN009 p16-Negative Results at ASTRO 2026
Chad Rusthoven
Principal Investigator SWOG Maverick Trial; Co-Principal Investigator NRG CC009
Carteret Healthcare; adjunct at University of Colorado and UNC Chapel Hill
Episode: NRG-CC009 and the MAVERICK Study at ASTRO 2026
Ted Hong
Physician and trial investigator discussing Gi003 results
NRG Oncology
Episode: NRG-GI003 Results in the ASTRO 2026 Plenary
George Zhao
Physician scientist focusing on computational biology and translational biomarkers
MD Anderson Cancer Center, Department of Genitourinary Radiation Oncology
Episode: The SPPORT Study Analysis Results at ASTRO 2026
Ying Liu
Gynecologic medical oncologist; lead investigator for NRG Oncology Gy036 at Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center
Episode: The NRG-GY036 Trial for Ovarian Cancer Month
Lauren Mell
Principal investigator of the NRG Oncology HN016 trial, head and neck cancer expert
University of California, San Diego
Episode: NRG-HN016: The "CONCISE" Study for Locoregionally Advanced Head and Neck Cancer Patients that are Unable to Take Cisplatin
Scott Delacroix
Urologic oncologist; medical director of urologic oncology at Mary Bird Perkins Cancer Center
Mary Bird Perkins Cancer Center
Episode: NRG-GU015, the "ARCHER" Study for Muscle Invasive Bladder Cancer
Himanshu Nagar
Genitourinary radiation oncology service chief at Memorial Sloan Kettering Cancer Center; new title: Manhattan Chief of Operations
Memorial Sloan Kettering Cancer Center
Episode: NRG-GU015, the "ARCHER" Study for Muscle Invasive Bladder Cancer

Hosts

Stephen Chun
Host of The NRG Oncology Podcast; co-leader of oncology conversations; specializes in radiation oncology context and trial design within NRG.
Lauren Henke
Co-host focusing on multidisciplinary cancer care, trial design, and policy-level discussions within oncology.

Reviews

4.8 out of 5 stars from 18 ratings
  • A must listen for anyone involved in the field of radiation medicine

    Drs. Chun and Henke do a masterful job of guiding the listener through the key aspects of the discussion.

    Apple Podcasts
    5
    Frustrated with Apple TV
    United Statesa year ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

High-quality, data-driven discussions that feel accessible to practitioners seeking real-world applications.
Guests bring practical clinical and operational insights for trial execution.
Experts host conversations with depth and clarity that help listeners grasp complex trial design.

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Talking Points

Recent interactions between the hosts and their guests.

NRG-BR002 Published in JCO
Q: How has the evolving systemic therapy landscape affected the interpretation of BR002?
The treatment landscape has changed dramatically since BR002 was initiated, with advances like CDK4-6 inhibitors and antibody-drug conjugates potentially influencing outcomes. However, BR002 still did not demonstrate a clear benefit from local therapies despite these advancements, suggesting that patient selection and underlying biology are crucial for identifying who might benefit.
NRG-BR002 Published in JCO
Q: Can you summarize what BR002 was designed to test and what the final results show?
BR002 was designed to test whether adding local therapies (stereotactic body radiotherapy or metastasectomy) to standard systemic therapy could improve progression-free and overall survival in oligometastatic breast cancer. The final results show that with longer follow-up, the trial remains negative for the primary endpoints, with no significant survival benefit across the overall population, though translational data hint at possible subgroups with biological signals.
The SPPORT Study Analysis Results at ASTRO 2026
Q: Can PAM50 be routinely used to guide hormone therapy for recurrent prostate cancer?
Yes, PAM50 has been validated in retrospective matched cohorts and two randomized trials, supporting its role as a predictive biomarker in this setting, though clinical use should still consider multiple factors and shared decision-making.
NRG-GI003 Results in the ASTRO 2026 Plenary
Q: With the results presented today, do you think patients should still be routinely offered proton therapy for hepatocellular carcinoma?
Dr. Hong indicated that current results do not support routinely preferring protons over photons for hepatocellular carcinoma, highlighting the advances in photon-based therapy and suggesting that protons may only be considered for a subset of patients, pending biomarker analyses like HGF.
NRG-GI003 Results in the ASTRO 2026 Plenary
Q: Can you fill us in on the major findings presented today on NRG Gi003 at the Astro 2026 plenary session?
Dr. Hong explained that there was no difference in outcomes between protons and photons, with both modalities delivering excellent disease control and safety. The trial's early closure for futility suggested no clear advantage of protons over photons in this hepatocellular carcinoma setting.

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Frequently Asked Questions About The NRG Oncology Podcast

What is The NRG Oncology Podcast about and what kind of topics does it cover?

This show centers on oncology, focusing on trial-design, translational science, and multidisciplinary patient care across a wide range of cancer types. Episodes frequently feature leaders from major cancer centers and cooperative groups discussing trial results, design rationale, regulatory and policy implications, patient advocacy, and real-world treatment trade-offs. The format blends deep clinical depth with practical insights into trial accrual, biomarker-driven strategies, and the intersection of research with health policy, making it valuable for clinicians, researchers, trial coordinators, and executives shaping cancer care. A notable strength is the density of expert guests who provide both clinical and operational perspectives, fro... more

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Which podcasts are similar to The NRG Oncology Podcast?

These podcasts share a similar audience with The NRG Oncology Podcast:

1. ASTRO Journals
2. JAMA Clinical Reviews
3. RadOnc Report
4. ACRO Podcast
5. Two Onc Docs

How many episodes of The NRG Oncology Podcast are there?

The NRG Oncology Podcast launched 2 years ago and published 54 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The NRG Oncology Podcast?

Recent guests on The NRG Oncology Podcast include:

1. Stephen Chimera
2. Paul Harari
3. Chad Rusthoven
4. Ted Hong
5. George Zhao
6. Ying Liu
7. Lauren Mell
8. Scott Delacroix

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