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The CAIO Connect Podcast (Chief AI Officer Connect Podcast)

Sanjay Puri
Artificial Intelligence
Agentic AI
Digital Transformation
Generative AI
Cybersecurity
Machine Learning
Sustainability
Change Management
Carbon Capture
Higher Education
Data Privacy
AI Transformation
AI Governance
AI Ethics
Ethics In AI
Data Governance
Innovation
Material Sciences
Responsible AI
Chief AI Officer

The CAIO Connect Podcast with Sanjay Puri Join tech entrepreneur, AI expert, and mentor Sanjay Puri as he delves into the world of AI leadership. Each episode unravels the challenges and triumphs faced by Chief AI Officers and dynamic founders, sharing insightful stories and experiences. Discover how these leaders attract top talent and drive innovation in AI and emerging technologies. Tune in for... more

PublishesTwice weeklyEpisodes91Founded2 years ago
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Artwork for The CAIO Connect Podcast

Latest Episodes

In this episode, Sanjay Puri speaks with Katya Andresen, Executive Vice President and Chief Data, Digital and AI Officer at The Cigna Group., about building enterprise AI at scale in one of the world's most complex and highly regulated industries. Ka... more

Recorded live at Zenith Live 2026 in Las Vegas, Sanjay Puri speaks with Sam Curry, Global VP & CISO at Zscaler, about the evolving relationship between AI leadership and cybersecurity. From Agentic AI and AI governance to cyber risk, AI ROI, workforc... more

Recorded live at Zenith Live in Las Vegas, Sanjay Puri speaks with Swami Kocherlakota, EVP of Agentic AI Engineering at Zscaler, about the rapidly evolving intersection of AI, cybersecurity, and enterprise transformation. Swami shares insights on age... more

Recorded live at Zenith Live in Las Vegas, Sanjay Puri speaks with Dhaval Sharma, Executive Vice President of Product Strategy at Zscaler, about AI agents, Zero Trust security, Shadow AI, enterprise governance, and the future of cybersecurity. Dhaval... more

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Recent Guests

GS Jha
Chief AI Officer and CISO at QuantumScape
QuantumScape
Episode: How Enterprise Leaders Are Securing AI Transformation | GS Jha, QuantumScape | TechX San Jose
Anjali Arora Mehra
Chief AI Officer at eBay, leads AI strategy and transformation
eBay
Episode: The AI Playbook Behind eBay’s Innovation | with Anjali Arora, eBay | Live at TechEX, San Jose
Nina Kottler
Chief Medical AI Officer, Mosaic Clinical Technologies
Mosaic Clinical Technologies / Radiology Partners
Episode: AI in Healthcare Is Bigger Than ChatGPT | Dr. Nina Kottler, Mosaic Clinical Technologies
Anton Bonifacio
Chief AI Officer and Chief Information Security Officer at Globe Telecom
Globe Telecom
Episode: Inside Globe Telecom’s 90% AI Adoption Journey | With Anton Reynaldo Bonifacio
Sam Fankuchen
Co-founder/CEO of Golden (a social impact venture focused on AI for good)
Golden
Episode: The Shadow Organization That Scales Without Sacrificing Trust | With Sam Fankuchen, Golden
Christine Todt
Senior Vice President of Cybersecurity at Mastercard
Mastercard
Episode: Mastercard Scores Trillion Data Points in 50ms - What It Means for AI Security | with Kiersten E. Todt
Steve Suarez
CEO of Horizon X, strategy work in quantum computing, AI, and innovation
Horizon X
Episode: There Is No Safe AI Future Without Getting Cybersecurity Right First | With Steve Suarez & Rebecca Kramer
Rebecca Kroffelmer
CEO of QSecure, cybersecurity specialist with a background in AI
QSecure
Episode: There Is No Safe AI Future Without Getting Cybersecurity Right First | With Steve Suarez & Rebecca Kramer
Taylor Stockton
Chief Innovation Officer, Department of Labor
Department of Labor
Episode: What the U.S. Department of Labor Wants Every CEO to Know About AI and Workers | With Taylor Stockton

Host

Sanjay Puri
Host of The CAIO Connect Podcast/ CAIO Connect

Reviews

5.0 out of 5 stars from 17 ratings
  • Interesting!

    Great topic. Nice podcast!

    Apple Podcasts
    5
    Eve Betsy
    Philippines2 years ago
  • Awesome!

    Such great episodes! The guest lineup and the host made this a must-listen. Perfect!

    Apple Podcasts
    5
    ish034
    Philippines2 years ago
  • Excellent Insights

    I look forward to every new episode of this podcast. Sanjay is a brilliant and insightful host!

    Apple Podcasts
    5
    HistoryDude1492
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

High-quality guest lineup and thoughtful host questioning
Host brings sharp, actionable insights for CIOs and CAIOs
Guests deliver governance and ROI-focused takeaways for large-scale AI programs
Content is consistently practical for sponsorship and partnership discussions
Profound examples of enterprise AI leadership from guests

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#217
Belgium/Technology

Talking Points

Recent interactions between the hosts and their guests.

The AI Playbook Behind eBay’s Innovation | with Anjali Arora, eBay | Live at TechEX, San Jose
Q: How should an organization look at ROI for AI?
ROI should be framed as a business outcome analysis, starting with a clear customer or business problem, identifying a North Star metric, and evaluating AI against tangible value like incremental revenue or cost savings, rather than just counting automated hours.
AI in Healthcare Is Bigger Than ChatGPT | Dr. Nina Kottler, Mosaic Clinical Technologies
Q: How do you determine whether a given AI tool should go into production in a clinical setting?
We evaluate clinically (acceptance by end users and impact on workflow), technically (scalability and infrastructure fit), and financially (ROI and value to patients and staff), ensuring the tool meaningfully improves care and efficiency.
AI in Healthcare Is Bigger Than ChatGPT | Dr. Nina Kottler, Mosaic Clinical Technologies
Q: What infrastructure is required to support AI at scale in healthcare, and what have you had to build at Mosaic?
We had to create cloud-native, AI-native infrastructure with robust data pipelines and lifecycle management; traditional on-prem setups failed to move data seamlessly, so we built an integrated, scalable system that supports rapid model deployment and real-world monitoring.
AI in Healthcare Is Bigger Than ChatGPT | Dr. Nina Kottler, Mosaic Clinical Technologies
Q: You pivoted from applied mathematics to medicine; what connected those fields for you and influenced your path into radiology AI?
The connective tissue was learning to make the best decision under real-world constraints; optimization theory taught me there are no absolute right answers, only the best balance of accuracy, time, cost, and patient outcomes in a messy, real-world environment.
How Enterprise Leaders Are Securing AI Transformation | GS Jha, QuantumScape | TechX San Jose
Q: What is your view on shadow AI and how should enterprises approach it?
Shadow AI is a risk to IP and governance; you need strong data governance, clear purpose for each tool, and human-in-the-loop oversight to ensure consistency and accountability across the organization.

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Frequently Asked Questions About The CAIO Connect Podcast

What is The CAIO Connect Podcast about and what kind of topics does it cover?

A forward-looking interview series focused on AI leadership in large organizations, governance, and practical deployment at scale. Conversations often center on enterprise AI strategy, data governance, security, agentic AI, and the workforce and policy implications of widespread AI adoption. Notable strengths include a strong emphasis on governance, risk management, and real-world ROI, with guests who hold top AI or CIO roles at major enterprises or government bodies. The format tends to blend strategic vision with hands-on lessons from large-scale AI programs, making it helpful for potential guests and brands seeking credible, enterprise-focused sponsorship.

Unique angles include governance frameworks for agentic AI, AI literacy across ro... more

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Which podcasts are similar to The CAIO Connect Podcast?

These podcasts share a similar audience with The CAIO Connect Podcast:

1. The AI Daily Brief: Artificial Intelligence News and Analysis
2. Business Wars

How many episodes of The CAIO Connect Podcast are there?

The CAIO Connect Podcast launched 2 years ago and published 91 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The CAIO Connect Podcast?

Recent guests on The CAIO Connect Podcast include:

1. GS Jha
2. Anjali Arora Mehra
3. Nina Kottler
4. Anton Bonifacio
5. Sam Fankuchen
6. Christine Todt
7. Steve Suarez
8. Rebecca Kroffelmer

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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