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Talking Precision Medicine

Genialis
Precision Medicine
Artificial Intelligence
AI In Healthcare
Oncology
Biotechnology
Digital Twins
Genomics
Life Sciences
Genialis
Clinical Trials
Biotech
Cancer Treatment
Cancer Immunotherapy
T-Cell Lymphoma
Cell Therapy
CAR T-Cell Therapy
Google Cloud
AI In Medicine
Gene Therapy
Drug Development

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you ... more

PublishesMonthlyEpisodes59Founded8 years ago
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Life SciencesScience

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Artwork for Talking Precision Medicine

Latest Episodes

Mental health remains one of medicine's greatest unmet needs. In this episode, Jacob Hooker explains how Sensorium Therapeutics is searching for new psychiatric medicines by combining traditional plant knowledge with cutting-edge drug development. Ja... more

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In episode 58, Rafael sits down with James Zanewicz, CEO of Connect, to discuss the art and science of building innovation ecosystems. From Connect's origins as the world's first accelerator to the future of AI-powered healthcare, James shares lesson... more

YouTube

In this episode, Rafael Rosengarten sits down with Lisa Gurry, Chief Business Officer at GeneDx, to discuss the transformative role of genomic testing in rare disease diagnosis, therapeutic discovery, and precision medicine. Lisa shares GeneDx's miss... more

In this episode, Rafael Rosengarten sits down with Dr. Kamal Jethwani, VP of Digital Ventures at Moffitt Cancer Center, CEO of AccelerOnc Studio, and consulting CEO of Decimal Health. With over two decades in digital health, Kamal shares how Moffitt ... more

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Recent Guests

Jacob Hooker
CEO of Sensorium Therapeutics
Sensorium
Episode: Jacob Hooker | From motifs to medicines: Harnessing nature’s pharmacopeia for novel CNS therapies | TPM podcast #59
James Zanewicz
CEO of Connect
Connect
Episode: James Zanewicz | Fostering innovation at scale: it’s all about the ecosystem | TPM podcast #58
Lisa Gurry
Chief Business Officer
GeneDx
Episode: Lisa Gurry | To Infinity and beyond: the future of comprehensive testing and genetic medicine | TPM podcast #57
Kamal Jethwani
VP of Digital Ventures at Moffitt Cancer Center; CEO of AccelerOnc Studio
Moffitt Cancer Center; AccelerOnc Studio
Episode: Kamal Jethwani | The concierge CEO: Incubating the next generation of digital oncology companies | TPM podcast #56
Shakti Ramkissoon
Vice President of Oncology at LabCorp
LabCorp
Episode: Shakti Ramkissoon | The Pulse of the Oncologist: Meeting clinicians and patients where they are to deliver precision medicine | TPM podcast #55
Sean Khozin
CEO Roundtable on Cancer (CEO RT) leader and data-sharing advocate
CEO Roundtable on Cancer (CEO RT)
Episode: Sean Khozin | The rhythm and dissonance of cancer biology | TPM podcast #54
Colette Delawalla
CEO of Stand Up For Science
Stand Up For Science
Episode: Colette Delawalla | Be the change you want to see in the world: mobilizing to protect American science | TPM podcast #53
Ian Simon
Head of Biotechnology at Aspis Intelligence
Aspis Intelligence
Episode: Ian Simon | When following the science isn’t enough: risk, communication, and the future of biotechnology | TPM podcast #52
Michelle Chen
CEO of Form Bio, focused on genetic medicines and genome engineering using AI.
Form Bio
Episode: Michelle Chen | Using AI to derisk gene therapy and genetic medicine | TPM podcast #51

Host

Rafael Rosengarten
CEO and co-founder of Genialis; Host of the show

Reviews

4.8 out of 5 stars from 10 ratings
  • Great conversations

    Absolutely my favorite podcast to host!

    Apple Podcasts
    5
    rafecooks
    United States3 years ago
  • Interesting topics

    Informative podcast by a great mind bringing on innovative guests.

    Apple Podcasts
    5
    Andrew Lange
    United States4 years ago
  • Interview with Leaders in the field

    Great take on precision medicine including bioinformatics, big data, cell therapy, and gene therapy.

    Apple Podcasts
    5
    JVSocclax
    United States7 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Thoughtful discussions that bridge science and industry
Great for understanding AI's role in precision medicine
High-quality guests with practical insights for biotech

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

Jacob Hooker | From motifs to medicines: Harnessing nature’s pharmacopeia for novel CNS therapies | TPM podcast #59
Q: What do you see for psychiatry 10 years from now?
Jacob envisions durable medicines that reduce daily dosing requirements, leveraging psychedelics and other modulators to rewire brain circuits and combine pharmacology with behavioral therapy for durable outcomes.
Jacob Hooker | From motifs to medicines: Harnessing nature’s pharmacopeia for novel CNS therapies | TPM podcast #59
Q: How do you approach synthesis and AI in medicinal chemistry for natural products?
They balance traditional medicinal chemistry with AI tools for synthesis planning and docking, but acknowledge current AI models struggle with complex natural-product scaffolds. They prioritize liability reduction and canonical drug development steps, using AI for prioritization but relying on chemist intuition for design.
Jacob Hooker | From motifs to medicines: Harnessing nature’s pharmacopeia for novel CNS therapies | TPM podcast #59
Q: What is the lead program and what are the next clinical steps?
The first program, Sense01 for anxiety, has begun in phase 1 with single ascending dose studies and biomarker tests; top-line data is expected soon, with two more programs in epilepsy and cognitive enhancement progressing toward clinic and IND-enabling steps.
Jacob Hooker | From motifs to medicines: Harnessing nature’s pharmacopeia for novel CNS therapies | TPM podcast #59
Q: Tell us about Sensorium and how it started.
Jacob describes Sensorium as a venture born from ethnobotany and the Center for the Neuroscience of Psychedelics, focusing on psychoactive natural products that are not party drugs. The company uses pattern discovery and knowledge graphs to connect plant-derived compounds with mechanisms and potential CNS indications, then develops derivatives to create practical, safe medicines.
Lisa Gurry | To Infinity and beyond: the future of comprehensive testing and genetic medicine | TPM podcast #57
Q: What does your day-to-day look like as Chief Business Officer at GeneDx, given the multiple moving parts of the healthcare system?
Lisa describes overseeing data products, biopharma partnerships, and marketing, while aligning operations to deliver testing, educate clinicians, and support families through the diagnostic journey.

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Frequently Asked Questions About Talking Precision Medicine

What is Talking Precision Medicine about and what kind of topics does it cover?

A tight focus on AI, big data, and digital health as they intersect with drug discovery and precision medicine. Episodes center on how data infrastructure, real-world evidence, and advanced analytics power better diagnostics, faster development, and scalable therapies, often through hospital-based ventures, centralized labs, or biotech partnerships. Noteworthy angles include practical adoption strategies in clinical programs, data sharing and governance, and the evolving regulatory landscape for AI-enabled therapeutics. The show frequently features senior leaders and trailblazers shaping the future of AI in healthcare, offering actionable insights for listeners building or sponsoring AI-driven health initiatives.

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How many listeners does Talking Precision Medicine get?

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Which podcasts are similar to Talking Precision Medicine?

These podcasts share a similar audience with Talking Precision Medicine:

1. Up First from NPR
2. This American Life

How many episodes of Talking Precision Medicine are there?

Talking Precision Medicine launched 8 years ago and published 59 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Talking Precision Medicine?

Recent guests on Talking Precision Medicine include:

1. Jacob Hooker
2. James Zanewicz
3. Lisa Gurry
4. Kamal Jethwani
5. Shakti Ramkissoon
6. Sean Khozin
7. Colette Delawalla
8. Ian Simon

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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