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Smith & Sheridan on Biotech

S&S Ltd.

Conversations on the science and business of Biotechnology with Andy Smith and Cormac Sheridan. To receive notifications when new episodes are published, email notifications@smithandsheridan.eu or follow us on LinkedIn.

PublishesWeeklyEpisodes27Founded4 months ago
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BusinessNewsNews CommentaryInvesting

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Latest Episodes

Ophthalmology has long been a fruitful area for biotechnology innovation. In highly prevalent conditions associated with ageing, such as age-related macular degeneration, or with chronic disease, such as diabetic macular oedema, vascular endothelial ... more

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7 days ago
YouTube

For all the extraordinary progress we have seen in basic biological research and in the development of advanced therapies, allergy is an area that seems to be stuck and badly in need of innovation. For some, an allergy may be little worse than an irr... more

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18 days ago
YouTube

A couple of years ago, PROTACs were ubiquitous. Start-ups were devising increasingly clever ways of making them, while large pharma companies were queuing up to tap into their expertise and their development programs. Proteolysis-targeting chimeras, ... more

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a month ago
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Over 10% of the world’s population – or 850 million people – are estimated to have kidney disease, and the problem is growing rapidly. The vast majority lives in low-income or low-and-middle-income countries, and, without access to primary healthcare... more

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a month ago
YouTube

Human longevity is a precious thing. Some people receive a tragically short amount of it. Others who have it in abundance want even more of it – and a reasonable chunk of the biopharmaceutical industry has organised itself around the goal of deliveri... more

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2 months ago
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Therapeutic cancer vaccines have had a long and chequered history. The BCG (Bacillus Calmette-Guérin) vaccine, originally developed to protect against tuberculosis in the 1920s, was adopted back in the 1970s as treatment for bladder cancer. When deli... more

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2 months ago
YouTube

The flow of money is a constant preoccupation of the biotechnology sector, because without it nothing gets done. So, whether the markets are up or down, and whether investors are buying or selling is important, even if it is secondary to the actual b... more

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2 months ago
YouTube

The failure of Relyvrio in a post-approval phase 3 study in amyotrophic lateral sclerosis (ALS) means its days as a commercial drug are probably numbered. It initially gained approval in Canada in June 2022 (where it is, confusingly, known as Albrioz... more

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3 months ago
YouTube

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