
Phages (bacteriophages) are viruses that kill bacteria with sniper-like precision. They can be incredibly useful for treating life-threatening infections ('phage therapy'), and can help us reduce our dependence on antibiotics. They've been known for 100 years... so WHY do we still not see them on the shelves? Jessica Sacher, PhD (Staff Scientist at Stanford and cofounder of Phage Directory) and Jo... more
| Publishes | Monthly | Episodes | 16 | Founded | a year ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Life SciencesScience | |||

“The thing everybody thinks is a tailwind for our space — the low financial barrier to get into a clinical trial — is actually one of the largest headwinds.”
Paul has spent 35 years in biopharma, and he has a sharp take on why phage therapy isn't pu... more
Chip Schooley (UC San Diego, IPATH) and Graham Hatfull (University of Pittsburgh) join us to discuss why phage therapy needs biologists and clinicians collaborating — and what the HIV field’s playbook can teach us.
Topics covered:
• Why they organiz... more
What does it take to build a phage therapy program from nothing — and keep your research lab running at the same time?
In this episode, Joe and I sat down with Dr. Daria Van Tyne, PhD, Associate Professor of Medicine at the University of Pittsburgh ... more
Can AI design living organisms from scratch? Samuel King and Claudia Driscoll from the Arc Institute used genome language models to generate functional phages—and 16 of them actually worked in the lab. Not only that, they killed bacteria equally or b... more
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The show centers on phage therapy, covering the scientific foundations of bacteriophages, translation to clinical use, and the regulatory and funding hurdles that shape what therapies reach patients. Episodes frequently feature researchers, clinicians, and biotech executives discussing topics like phage design and delivery, PK/PD in trials, regulatory pathways, compassionate-use cases, manufacturing and quality control, and the evolving business landscape around phage companies. A notable strength is bringing practical, practitioner-level perspectives—from academic labs to startup leadership—often with clear takeaways on how to advance phage therapy from concept to clinic. This mix makes it valuable for scientists, healthcare professionals,... more
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Recent guests on Podovirus include:
1. Paul Garofolo
2. Chip Schooley
3. Graham Hatfull
4. Daria Van Tyne
5. Samuel King
6. Claudia Driscoll
7. Dr. Saima Aslam
8. Steven Theriault
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