Rephonic
Artwork for Podovirus
Phage Therapy
Antimicrobial Resistance
Prosthetic Joint Infections
Clinical Trials
Antibiotic Resistance
Eligo Biosciences
Intralytix
Phage-Inducible Chromosomal Islands
Cytophage
Microbiome
Base Editing
Mayo Clinic
Biofilms
Food Safety
Vancomycin-Resistant Enterococci
FDA
Mobile Genetic Elements
AI In Scientific Research
Diabetic Foot Ulcers
Eliava Center

Phages (bacteriophages) are viruses that kill bacteria with sniper-like precision. They can be incredibly useful for treating life-threatening infections ('phage therapy'), and can help us reduce our dependence on antibiotics. They've been known for 100 years... so WHY do we still not see them on the shelves? Jessica Sacher, PhD (Staff Scientist at Stanford and cofounder of Phage Directory) and Jo... more

PublishesMonthlyEpisodes12Founded7 months ago
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Life SciencesScience

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"When I first started, I was treating anything and everything in terms of ‘this is highly drug resistant and it's failed’. But I think I have a clearer idea now, at least clinically, where I think phage would be beneficial, rather than all comers.”

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"It's unacceptable to just tell this poor patient, there's nothing I can do to help you... That's when I thought, okay, well, what about kind of pushing the boundaries a bit here and thinking about phage therapy?" - Dr. Marisa Azad

Join us for an in... more

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"Phages are not drugs. Every time they say, 'Did you go through regulatory?' I say, 'I can do regulatory, but I'm not a drug.' There's 145 components of the regulatory requirements that I don't fit in."

When your health innovation doesn't fit existi... more

YouTube

"This feels just like the early days of the HIV crisis. People are dying, you're not hearing about it. We need a group like ACT UP to bring this to the public. We're not going to get phage therapy until people start demanding we have it."

On this e... more

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Similar Podcasts

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PhageCast
PhageCastNews and interviews on the phage field.

Recent Guests

Dr. Saima Aslam
Professor of Medicine at University of California, San Diego and clinical lead at the Center for Innovative Phage Application and Therapeutics
University of California, San Diego
Episode: How to get successful outcomes with phage therapy: Saima Aslam, MD, MS
Steven Theriault
CEO of Cytophage, a Canadian company specializing in phage therapy
Cytophage
Episode: How to navigate regulatory limbo: a Canadian phage therapy CEO's playbook
Chris Shaffer
A retired high school principal and phage therapy advocate
Episode: Why can't patients access phage therapy? Does FDA need to change, or do patients just need a voice?
Jonathan Solomon
CEO of BiomX
BiomX
Episode: Finally, phase 2 data! Inside BiomX's successful phage therapy trial with CEO Jonathan Solomon
José Penadés
Professor at Imperial College London, working on mobile genetic elements.
Imperial College London
Episode: Does every scientist need an AI co-scientist? How two professors solved a years-long viral mystery
Tiago Costa
Professor at Imperial College London, expert in structural biology and conjugation.
Imperial College London
Episode: Does every scientist need an AI co-scientist? How two professors solved a years-long viral mystery
Dr. Alexander Sulakvelidze
Co-founder of Intralytix and a pivotal figure in phage therapy
Intralytix
Episode: How to bring phages to market: Intralytix's food-to-pharma strategy
Gina Suh
Infectious diseases physician at the Mayo Clinic
Mayo Clinic
Episode: Gina Suh, MD: What it's really like to treat patients with phage therapy
Jesus Fernandez
CEO of Eligo Biosciences, specializing in microbiome gene editing
Eligo Biosciences
Episode: Jesus Fernandez-Rodriguez: How Eligo Bioscience edits gut bacteria with phages

Hosts

Jessica Sacher
Co-host of the podcast, Staff Scientist at Stanford and cofounder of Phage Directory.
Joseph Campbell
Co-host of the podcast, former NIAID program officer.

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How to get successful outcomes with phage therapy: Saima Aslam, MD, MS
Q: What role does pre-selection play in treating patients with phage therapy?
One of the things I have learned is there's been a lot of interest in using phage for multidrug-resistant pseudomonas cardiac device infections.
How to get successful outcomes with phage therapy: Saima Aslam, MD, MS
Q: How do you see patient selection changing now that phage therapy is more established?
With more awareness, there's definitely a lot of interest everywhere and the availability of phage that we can use for patients now is very limited.
How to get successful outcomes with phage therapy: Saima Aslam, MD, MS
Q: What do you think you've, what do you wish you had known when you were doing your first case that you feel like you now know?
I think I have a clear idea now, at least clinically, where I think phage would be beneficial rather than all comers.
How to bring phages to market: Intralytix's food-to-pharma strategy
Q: What do you think are the biggest challenges for phage therapy moving forward?
The major issue is establishing proof of efficacy through rigorous clinical trials.
How to bring phages to market: Intralytix's food-to-pharma strategy
Q: Where have you seen the field change the most since you started?
The interest in phage therapy has increased dramatically, with more publications and regulatory approvals.

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Frequently Asked Questions About Podovirus

What is Podovirus about and what kind of topics does it cover?

The content explores the emerging field of phage therapy, focusing on bacteriophages—viruses that target and kill bacteria with high specificity. Various episodes feature insights from experts in medicine, academia, and biotechnology, discussing both clinical applications and the challenges that phage therapy faces, such as regulatory hurdles and public awareness. Noteworthy themes include the urgent need for innovative solutions to combat multidrug-resistant infections, the potential of phages in treating complex cases, and the intersection of science and patient experience. The podcast uniquely sheds light on personal stories that underscore systemic issues in healthcare, making it appealing to those interested in the future of medicine, ... more

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These podcasts share a similar audience with Podovirus:

1. PhageCast

How many episodes of Podovirus are there?

Podovirus launched 7 months ago and published 12 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Podovirus?

Recent guests on Podovirus include:

1. Dr. Saima Aslam
2. Steven Theriault
3. Chris Shaffer
4. Jonathan Solomon
5. José Penadés
6. Tiago Costa
7. Dr. Alexander Sulakvelidze
8. Gina Suh

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