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NeuroFrontiers

Practical Neurology
Dravet Syndrome
Cervir-Vinersen
Clinical Trials
Seizure Frequency
Neurological Conditions
Genomic Testing
Behavior
Cognition
Phase 1-2a Study
Pediatric Epilepsy
Vineland 3
Open-Label Extension Studies
Parkinson's Disease
Epilepsy
Bioelectronic Medicine
Vagus Nerve Stimulation
Natural History Study
Pediatric Epilepsy Center Of Excellence
Medication Management
Hospital Care Standards

Practical Neurology partners with ReachMD to bring you clinical research and advancements that further clinicians' ability to diagnose and treat neurologic conditions.

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Latest Episodes

Jae W. Song, MD, MS, Associate Professor of Radiology at the University of Pennsylvania, Philadelphia, PA, discusses the diagnostic value of intracranial vessel wall MRI for vasculitis, as well as when clinicians should order this imaging technique a... more

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Riley Bove, MD, UCSF School of Medicine, San Francisco, CA details results from the MINORE and SOPRANINO studies examining Ocrevus treatment in pregnant and lactating women with multiple sclerosis.

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Beth McQuiston, MD, RD, Medical Director, Abbott, Abbott Park, IL, and David Okonkwo, MD, PhD, Professor of Neurological Surgery, University of Pittsburgh, Pittsburg, PA, describe some of the important updates to guidelines for the assessment of trau... more

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Jack Reeves, PhD, researcher at the University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, discusses results of a study which demonstrated high efficacy disease-modifying therapies may help prevent the development of pa... more

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Recent Guests

Jack Reeves
PhD researcher at the University of Buffalo Jacobs School of Medicine and Biomedical Sciences
University of Buffalo Jacobs School of Medicine and Biomedical Sciences
Episode: The Impact of High Efficacy DMTs on Paramagnetic Rim Lesions
Peter Pronovost
Chief Quality and Transformation Officer at University Hospitals Cleveland Medical Center
University Hospitals Cleveland Medical Center
Episode: Proposed Hospital Standards for Parkinson Disease Care Aim to Avoid Preventable Harm
Joseph Sullivan
Professor of Neurology and Pediatrics at the University of California San Francisco, director of the Pediatric Epilepsy Center of Excellence
UCSF School of Medicine
Episode: Promising Results for Investigational Antisense Oligonucleotide Treatment for Dravet Syndrome
Stavros Zanos
Associate Professor at the Institute of Bioelectronic Medicine
Feinstein Institutes for Medical Research
Episode: Vagus Nerve Stimulation: Effects Beyond the Nervous System
Paul Kruszka
Chief Medical Officer at GeneDx, clinician, and clinical geneticist
GeneDx
Episode: The Role of Advanced Genomic Testing in the Diagnosis and Treatment of Neurologic Conditions

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Talking Points

Recent interactions between the hosts and their guests.

Promising Results for Investigational Antisense Oligonucleotide Treatment for Dravet Syndrome
Q: What about some of the side effects that we're seeing with this treatment?
Dr. Sullivan notes that the treatment has been well tolerated overall, with uncommon procedural-related adverse events and some elevations in CSF protein observed, but without concerning symptoms manifesting in patients.
Promising Results for Investigational Antisense Oligonucleotide Treatment for Dravet Syndrome
Q: Can you please provide an overview of the open-label extension studies of Cervir-Vinersen as a potential treatment for patients with Dravet syndrome?
Dr. Sullivan discusses the cautious start with low doses in the Phase I-IIa study, escalating to higher doses to ensure safety and tolerability, while also aiming to treat seizure and non-seizure related comorbidities.
Vagus Nerve Stimulation: Effects Beyond the Nervous System
Q: Would VNS be a first line treatment or as part of adjunctive treatment for some of these conditions?
Current thinking is that it would be an adjunct measure alongside other treatments due to the multifactorial nature of these diseases.
Vagus Nerve Stimulation: Effects Beyond the Nervous System
Q: Could you explain how to properly stimulate the vagus nerve here?
The study of proper stimulation is ongoing, with a focus on specific anatomical arrangements within the vagus nerve to enhance treatment efficacy while reducing side effects.
The Impact of High Efficacy DMTs on Paramagnetic Rim Lesions
Q: What do you think are the future directions for research in this area?
Future research should focus on developing new therapies targeting chronic active lesions, improving consensus for PRL detection, and understanding the factors influencing PRL formation.

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Frequently Asked Questions About NeuroFrontiers

What is NeuroFrontiers about and what kind of topics does it cover?

Focusing on advances in the field of neurology, the content explores critical research findings and clinical practices that enhance the diagnosis and treatment of neurological disorders. Episodes cover a range of topics including the latest in disease-modifying therapies, hospital care standards for specific conditions like Parkinson's disease, and the implications of genomic testing for various neurological conditions. The discussions often feature expert insights that aim to improve patient care, safety, and overall treatment outcomes in clinical practices, making it a valuable resource for clinicians interested in cutting-edge developments in neurology.

The unique emphasis on practical applications of research findings makes this series... more

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Which podcasts are similar to NeuroFrontiers?

These podcasts share a similar audience with NeuroFrontiers:

1. Practical Neurology Podcast
2. Neurology® Podcast
3. Neurology Exam Prep Podcast

How many episodes of NeuroFrontiers are there?

NeuroFrontiers launched 2 years ago and published 11 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact NeuroFrontiers?

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What guests have appeared on NeuroFrontiers?

Recent guests on NeuroFrontiers include:

1. Jack Reeves
2. Peter Pronovost
3. Joseph Sullivan
4. Stavros Zanos
5. Paul Kruszka

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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