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NeuroFrontiers

Practical Neurology
Multiple Sclerosis
Dravet Syndrome
Cervir-Vinersen
Seizure Frequency
Clinical Trials
Genomic Testing
Neurological Conditions
Vineland 3
Open-Label Extension Studies
Cognition
Behavior
Pediatric Epilepsy
Phase 1-2a Study
Parkinson's Disease
Intracranial Vessel Wall MRI
Ocrelizumab
MOGAD
Satralizumab
Alzheimer's Disease
Epilepsy

Practical Neurology partners with ReachMD to bring you clinical research and advancements that further clinicians' ability to diagnose and treat neurologic conditions.

PublishesMonthlyEpisodes14Founded3 years ago
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Artwork for NeuroFrontiers

Latest Episodes

In this episode, Luka Kulic, MD, Vice President and Global Head of Early Clinical Development in Neuroscience and Rare Diseases at Roche, Basel, Switzerland, discusses the investigational Brainshuttle technology, including results from the BrainShutt... more

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Episode Description: What do the latest METEOROID trial results mean for neurologists treating myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD)? Michael Levy, MD, Massachusetts General Hospital, Boston, MA, discusses relapse pr... more

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Richard J. Nowak, MD, MS, Associate Professor of Neurology, Yale School of Medicine, Yale University, New Haven, CT and global principal investigator of the Myasthenia Gravis Inebilizumab Trial (MINT), discusses the phase 3 results, highlighting the ... more

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Riley Bove, MD, UCSF School of Medicine, San Francisco, CA details results from the MINORE and SOPRANINO studies examining Ocrevus treatment in pregnant and lactating women with multiple sclerosis.

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Recent Guests

Luka Kulic
Neurologist and neuroscientist, Vice President and Global Head of Early Clinical Development in Neuroscience and Rare Diseases at Roche
Roche
Episode: Next-Generation CNS Drug Delivery: Brainshuttle Technology and Clinical Implications in Alzheimer Disease
Michael Levy
World-renowned MOGAD expert
Massachusetts General Hospital
Episode: Advancing MOGAD Care
Richard Nowak
Dr. Nowak, Yale School of Medicine; Associate Professor of Neurology
Yale School of Medicine
Episode: Generalized Myasthenia Gravis: Inside the MINT Trial and CD19 B-Cell Therapy Advances
Riley Bove
MS Neurologist, Associate Professor at UCSF
University of California, San Francisco
Episode: Ocrevus Treatment in Pregnant and Lactating Women with Multiple Sclerosis
Jae Song
Associate Professor of Radiology at the University of Pennsylvania
University of Pennsylvania
Episode: The Use of Intracranial Vessel Wall MRI for the Diagnosis of Vasculitis
Jack Reeves
PhD researcher at the University of Buffalo Jacobs School of Medicine and Biomedical Sciences
University of Buffalo Jacobs School of Medicine and Biomedical Sciences
Episode: The Impact of High Efficacy DMTs on Paramagnetic Rim Lesions
Peter Pronovost
Chief Quality and Transformation Officer at University Hospitals Cleveland Medical Center
University Hospitals Cleveland Medical Center
Episode: Proposed Hospital Standards for Parkinson Disease Care Aim to Avoid Preventable Harm
Joseph Sullivan
Professor of Neurology and Pediatrics at the University of California San Francisco, director of the Pediatric Epilepsy Center of Excellence
UCSF School of Medicine
Episode: Promising Results for Investigational Antisense Oligonucleotide Treatment for Dravet Syndrome
Stavros Zanos
Associate Professor at the Institute of Bioelectronic Medicine
Feinstein Institutes for Medical Research
Episode: Vagus Nerve Stimulation: Effects Beyond the Nervous System

Chart Rankings

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Talking Points

Recent interactions between the hosts and their guests.

Generalized Myasthenia Gravis: Inside the MINT Trial and CD19 B-Cell Therapy Advances
Q: Can you tell us about the enrolled population and how it reflects everyday clinical practice?
The trial enrolled generalized MG patients with either ACHR or MUSK antibody positivity, most of whom had active disease and were on background therapies, making the population representative of real-world neuromuscular clinics.
Next-Generation CNS Drug Delivery: Brainshuttle Technology and Clinical Implications in Alzheimer Disease
Q: How does Brainshuttle compare with other methods of delivering large molecules across the blood-brain barrier?
Brainshuttle actively transports therapeutics via the transferrin receptor pathway, achieving rapid, widespread, and homogeneous brain penetration compared with standard antibodies, which limits brain access. This allows for lower doses and broader distribution, potentially improving efficacy while maintaining a favorable safety profile.
Ocrevus Treatment in Pregnant and Lactating Women with Multiple Sclerosis
Q: What are the implications for clinical practice?
These results provide concrete, product-specific safety data that reassure clinicians and patients about administering ocrelizumab to pregnant or lactating women, support informed discussions with families, and suggest that postpartum treatment decisions can be made with greater confidence about infant exposure and health outcomes.
Ocrevus Treatment in Pregnant and Lactating Women with Multiple Sclerosis
Q: What were the results from the Sopranino study?
The Sopranino study found that ocrelizumab transferred negligibly into breast milk and was undetectable in infant serum, with babies showing normal B-cell counts around 30 days after maternal treatment and no unexpected infections.
Ocrevus Treatment in Pregnant and Lactating Women with Multiple Sclerosis
Q: What were the results of the Minore study?
The Minore study enrolled pregnant women with MS in the second trimester and followed them through pregnancy, showing that none of the babies had B-cell levels below the lower limit of normal at six weeks, and that ochralizumab was largely undetectable in maternal and cord blood at birth, indicating limited placental transfer.

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Frequently Asked Questions About NeuroFrontiers

What is NeuroFrontiers about and what kind of topics does it cover?

Focusing on advances in the field of neurology, the content explores critical research findings and clinical practices that enhance the diagnosis and treatment of neurological disorders. Episodes cover a range of topics including the latest in disease-modifying therapies, hospital care standards for specific conditions like Parkinson's disease, and the implications of genomic testing for various neurological conditions. The discussions often feature expert insights that aim to improve patient care, safety, and overall treatment outcomes in clinical practices, making it a valuable resource for clinicians interested in cutting-edge developments in neurology.

The unique emphasis on practical applications of research findings makes this series... more

Where can I find podcast stats for NeuroFrontiers?

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Which podcasts are similar to NeuroFrontiers?

These podcasts share a similar audience with NeuroFrontiers:

1. Practical Neurology Podcast
2. American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM)

How many episodes of NeuroFrontiers are there?

NeuroFrontiers launched 3 years ago and published 14 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact NeuroFrontiers?

Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.

Where can I see ratings and reviews for NeuroFrontiers?

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What guests have appeared on NeuroFrontiers?

Recent guests on NeuroFrontiers include:

1. Luka Kulic
2. Michael Levy
3. Richard Nowak
4. Riley Bove
5. Jae Song
6. Jack Reeves
7. Peter Pronovost
8. Joseph Sullivan

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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