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Artwork for MODCAST
Preterm Birth
Preeclampsia
March Of Dimes
Vaginal Microbiome
Texas Collaborative Prematurity Research Center
Spontaneous Preterm Birth
Human Milk
Human Milk Oligosaccharides
Doulas
APOL1 Variant
Blood Type (ABO)
Pregnancy On a Chip
Premature Birth / Preterm Birth
Aspirin
Zebrafish
Hif-2
Indicated Preterm Birth
Non-Invasive Prenatal Testing
Electronic Medical Records
Cell-Free Fetal DNA

MODCAST is a podcast on the most impactful maternal and infant health research conducted today. MODCAST aims to bring scientists, doctors, donors, and families behind the laboratory doors for a fascinating look into the science that is changing, study by study, the story of moms and babies in the U.S. From interviews and news analysis to study discussions and more, MODCAST is the science community... more

PublishesMonthlyEpisodes39Founded3 years ago
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Life SciencesScience

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Artwork for MODCAST

Latest Episodes

Dr. Christina Megli, a 2025 March of Dimes Basil O’Connor Starter Scholar Research Award winner, discusses her discovery of 'first responder' macrophage immune cells in the amniotic sac in healthy pregnancy — a finding that may one day lead to new ri... more

Dr. Brice Gaudillière, an investigator at the March of Dimes Prematurity Research Center at Stanford, on an upcoming Randomized Controlled Trial he is heading that will test two common over the counter drugs — Aspirin and Prevacid, an acid reflux med... more

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Dr. Frank Lee, a Professor of Pathology and Laboratory Medicine at the University of Pennsylvania Perelman School of Medicine and a 2026 winner of a March of Dimes Discovery Grant, discusses his research on HIF2 gene suppression as a way to treat pre... more

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Dr. Thomas Jansson, the 2026 winner of the March of Dimes Agnes Higgins Award in Maternal-Fetal Nutrition, the Vice Chair of Research for the University of Colorado Anschutz Department of Obstetrics and Gynecology and the department’s Florence Crozie... more

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Recent Guests

Brice Gaudillière
Stanford PRC investigator; senior scientist; associate professor
Stanford Medicine; March of Dimes Prematurity Research Center at Stanford
Episode: Dr. Brice Gaudillière on the Potential of Aspirin + Lansoprazole to Stop Preterm Birth: A New Clinical Trial
Frank Lee
Professor of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine
University of Pennsylvania Perelman School of Medicine
Episode: Dr. Frank Lee on Why Tibetan Genes May Help Us Beat Preeclampsia
Thomas Jansson
Placental scientist, University of Colorado Anschutz Medical Campus
University of Colorado Anschutz Medical Campus
Episode: Dr. Thomas Jansson on the Placenta and Fetal Growth
Leonard Zon
Director of the Stem Cell Research Program at Boston Children's Hospital; Grousbeck Professor of Pediatric Medicine at Harvard Medical School
Boston Children's Hospital; Harvard Medical School
Episode: Dr. Leonard Zon on the Secrets of the Zebrafish
Tomiko Oskotsky
Integral part of The March of Dimes Prematurity Research Center at UCSF; co-directs the Database for Preterm Birth Research
University of California, San Francisco / March of Dimes Prematurity Research Center
Episode: Dr. Tomiko Oskotsky on the Big Moment for March of Dimes Data
Rupsa Boelig
Maternal-fetal medicine specialist
Thomas Jefferson University, Philadelphia
Episode: Dr. Rupsa Boelig on Aspirin Dosing for High-Risk Pregnant Women
Dr. Catherine Spong
Professor and Chair, Department of Obstetrics and Gynecology, UT Southwestern Medical Center
UT Southwestern Medical Center
Episode: Dr. Catherine Spong on the New Texas Collaborative Prematurity Research Center
Ramkumar Menon
Professor and Director, Division of Basic and Translational Research in Obstetrics and Gynecology
University of Texas Medical Branch at Galveston (UTMB)
Episode: Dr. Ramkumar Menon on the New Texas Collaborative Prematurity Research Center
Lynne Sykes
Co-director of the March of Dimes Prematurity Research Center at Imperial College London
Imperial College London / March of Dimes
Episode: Dr. Lynne Sykes on A New Link Between Blood Type and Preterm Birth

Host

Olesya Plouhi
Host of MODCAST (MODCAST)

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Talking Points

Recent interactions between the hosts and their guests.

Dr. Tomiko Oskotsky on the Big Moment for March of Dimes Data
Q: Tell me what it was like when you learned that the NAIRR data set was selected and recognized.
It was incredibly thrilling and validating, because the data had to meet a stringent AI-ready checklist and the NSF nomination acknowledged the quality and potential impact of our work in advancing preterm birth research.
Dr. Brice Gaudillière on the Potential of Aspirin + Lansoprazole to Stop Preterm Birth: A New Clinical Trial
Q: What evidence supports moving toward a clinical trial?
Digital twin predictions showed significant potential (up to 15-fold greater effect on prolonging gestation with the drug combination in simulations), validated by mouse models and prior data on drug safety in pregnancy, justifying the clinical transition
Dr. Brice Gaudillière on the Potential of Aspirin + Lansoprazole to Stop Preterm Birth: A New Clinical Trial
Q: How does the digital twin work and what data does it use?
The digital twin is built from single-cell immune data collected from pregnant women; it uses SITOF cytometry data, trained algorithms, and in vitro drug exposure experiments to predict how each cell would respond to drugs inside a real patient
Dr. Brice Gaudillière on the Potential of Aspirin + Lansoprazole to Stop Preterm Birth: A New Clinical Trial
Q: What is the basic setup of the RCT and who are the key players?
The trial tests aspirin and lansoprazole in two arms (intervention vs placebo) within a randomized design, with a digital twin technology screening and selecting responders to the treatment, making the study more efficient and targeted.
Dr. Lynne Sykes on A New Link Between Blood Type and Preterm Birth
Q: What is the FLIPTO trial and what are they hoping to learn?
FLIPTO is a placebo-controlled randomized trial using Lactin V (Lactobacillus crispatus) to flip the vaginal flora and assess effects on microbiome, immune response, and preterm birth rates, with broader implications for precision prevention.

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Frequently Asked Questions About MODCAST

What is MODCAST about and what kind of topics does it cover?

MODCAST consistently centers on cutting-edge maternal and infant health research, featuring clinicians, scientists, and policy-focused guests who translate complex biology into real-world implications for moms and babies. Across recent episodes, listeners encounter deep dives into placental signaling and fetal growth, aspirin strategies for high-risk pregnancies, innovative modeling of pregnancy through organ-on-a-chip technologies, and evidence-based discussions about doulas and postpartum support. The show frequently threads translational science with practical healthcare implications, highlighting how novel discoveries could shift clinical practice, trial design, and health equity in obstetrics. A notable strength is its ability to conne... more

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How many listeners does MODCAST get?

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What are the audience demographics for MODCAST?

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How many subscribers and views does MODCAST have?

To see how many followers or subscribers MODCAST has on Spotify and other platforms such as Castbox and Podcast Addict, simply upgrade your account. You'll also find viewership figures for their YouTube channel if they have one.

Which podcasts are similar to MODCAST?

These podcasts share a similar audience with MODCAST:

1. The Ezra Klein Show

How many episodes of MODCAST are there?

MODCAST launched 3 years ago and published 39 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact MODCAST?

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What guests have appeared on MODCAST?

Recent guests on MODCAST include:

1. Brice Gaudillière
2. Frank Lee
3. Thomas Jansson
4. Leonard Zon
5. Tomiko Oskotsky
6. Rupsa Boelig
7. Dr. Catherine Spong
8. Ramkumar Menon

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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