Latent Space: The AI Engineer Podcast

Latent.Space

Openai

Machine Learning

AI Engineering

AI Agents

Artificial Intelligence

Anthropic

AI Research

Reinforcement Learning

Natural Language Processing

AI Models

AI Engineer World's Fair

Synthetic Data

Transformers

Computer Vision

API

AI Safety

MCP

Generative AI

Open Source

Language Models

The podcast by and for AI Engineers! In 2025, over 10 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0. We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the de... more

391 ratings

Publishes	Twice weekly	Episodes	221	Founded	4 years ago
Number of Listeners		Categories	TechnologyScience

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Guests Hosts Reviews Charts Talking Points

Latest Episodes

🔬“We have foundation models for language, not for physics” — Anima Anandkumar, Bren Professor of Computing

A few years ago, Caltech Prof. and co-founder of Accelerated Understanding, Anima Anandkumar set out to develop the first open-source weather model with AI. Talking to experts in the field, she was met with skepticism. Weather is chaotic, physics sim... more

26 Aug 2026 • 1 hr 23 min

Simulation: the new Scaling Law — Joon Sung Park, Simile AI

When we first dicsussed the Summer of Simulative AI in 2024 we knew it would be a brief summer, but it has recently come back with a vengeance with SimGym in April and now Simile AI’s $2B Series B, backed by GreenOaks and Index Ventures with prominen... more

21 Aug 2026 • 1 hr 9 min • Most popular

🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery

This January, four big AI × Pharma tools deals were announced at the huge JPM Pharma conference that takes over San Francisco every year. OpenAI-backed Chai Discovery (now worth $4B) was somehow at the heart despite being all of 2 years old.

The Sc... more

11 Aug 2026 • 1 hr 35 min

The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten

Watch the full episode on YouTube:

We first covered Baseten last year when DeepSeek mania was at peak hype. Now they have raised a monster $13B round and become one of the new cohort of AI Infra decacorns that are (with Nvidia, Intel, and the semis ... more

3 Aug 2026 • 1 hr 41 min

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Recent Guests

Anima Anandkumar

Bren Professor of Computing at Caltech, AI for Science researcher

California Institute of Technology

Episode: 🔬“We have foundation models for language, not for physics” — Anima Anandkumar, Bren Professor of Computing

Joon Sung Park

Co-founder of Simile AI, researcher turned entrepreneur

Simile AI

Episode: Simulation: the new Scaling Law — Joon Sung Park, Simile AI

Neil Patil

Head of platform and product, Chai Discovery

Chai Discovery

Episode: 🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery

Matt McPartlon

Co-founder, Chai Discovery

Chai Discovery

Episode: 🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery

Philip Kiely

Affiliated with Inference Engineering and Baseten

Inference Engineering / Baseten

Episode: The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten

Ali Taha

Affiliated with Baseten

Baseten

Episode: The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten

Akshay Nathan

Lead Core Product Engineering at OpenAI; featured guest discussing ChatGPT Work and Codex

OpenAI

Episode: Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI

Eiso Kant

Co-founder/CEO of Poolside

Poolside

Episode: Inside the Model Factory — Eiso Kant, Poolside AI

Bo Wang

SVP and head of biomedical AI at Xaira Therapeutics

Xaira Therapeutics

Episode: 🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)

Hosts

Vibhu

Host of Latent Space: The AI Engineer Podcast; frequently introduces guests and guides conversations.

RJ Haneki

CTO of Miraomics; co-host and guest facilitator in multiple episodes.

Brandon Anderson

Guest/host on the show; co-host; involved in Latent Space AR for Science; appears across multiple lineups.

Reviews

4.7 out of 5 stars from 391 ratings

Sometimes interesting chats but frequently very visual and they don't describe what they show. Not a podcast.
Podcast Addict
2
kretyn
a month ago
I could hardly understand the speaker being interviewed.
Podcast Addict
2
yop host jnr
3 months ago
Soft interviews or fan ads
Interesting and relevant content, but couldn’t get past the interviews with frontier AI engineers feeling like softball ads. Maybe it’s just what we get with all OpenAi etc interviews is this pedaling their wares but soft leading questions makes it feel like 1hr of product hyping.
Apple Podcasts
3
Smashing kittens
Australia5 months ago
Insightful, but Hard to Follow Sans Context
The discussions on this podcast are potentially insightful, but after four episodes, I'm frustrated. The hosts and guests often launch into deep conversations using industry acronyms and company-specific news without providing any necessary context for the average listener. This lack of consideration makes the show difficult to follow and defeats the purpose of learning. They need to prioritize context for the audience.
Apple Podcasts
2
chief_rocka
United States10 months ago
Immediate Impact
I love this podcast as I I pretty much walk away from every show with something I can apply in my work!
Apple Podcasts
5
Willm50
United Statesa year ago

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Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Some episodes are hard to follow due to heavy industry jargon; listeners crave more context.

Consistently strong on technical depth and real-world implications of AI tooling.

The show is a go-to for AI engineers who want deep dives and practical takeaways.

A mix of highly actionable content and strong open-source/open-research perspectives.

Listeners praise practical, applicable insights and high-quality guest lineups.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts	#59	United States/Technology
Apple Podcasts	#28	United Kingdom/Technology
Apple Podcasts	#40	Canada/Technology
Apple Podcasts	#56	France/Technology
Apple Podcasts	#60	Germany/Technology
Apple Podcasts	#67	Australia/Technology

Talking Points

Recent interactions between the hosts and their guests.

Simulation: the new Scaling Law — Joon Sung Park, Simile AI

Q: What questions would a customer ask, and how do you customize a model for them?

Customers typically describe a population they care about, then they model that population using environments like surveys or behavioral experiments to run concept testing, focus groups, or even simulate earnings calls for public companies; they build population-level and individual-level models and tailor data collection to the target group.

⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build

Q: How do you envision pricing evolving for AI-enabled SaaS and enterprise products?

Pricing will likely combine subscriptions, per-user entitlements, and flexible consumption meters, with outcomes-based pricing remaining an option for customers who value demonstrable results.

⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build

Q: What are the key learnings from deploying frontier AI inside a large organization like Microsoft?

Deployment taught us that real-world value hinges on private evaluations, enterprise-grade harnesses, and the ability to tailor the model to specific traces and workflows, rather than chasing single benchmarks.

Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs

Q: What motivated the move from Vending Bench to multi-agent CEO-style setups?

The team wanted to push beyond a single agent, exploring parallelization, memory sharing, and economic decision-making to see how agents manage multiple threads and oversee a business.

Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs

Q: How did you get Anthropic involved early on?

They originally did evals with Anthropic as an early customer, which led to the idea of publishing public benchmarks rather than keeping it internal.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Latent Space: The AI Engineer Podcast

What is Latent Space: The AI Engineer Podcast about and what kind of topics does it cover?

A technically focused show featuring in-depth conversations with AI engineers, researchers, and startup founders who are deploying and building next‑gen AI systems. Episodes frequently center on open inference, production-grade AI tooling, model deployment, and scalable infrastructure, with a heavy emphasis on practical engineering details, real-world bottlenecks, and open vs closed approaches. Guests span inference tooling, AI hardware trends, open research, AI-enabled biotech, and advanced math tooling, offering both strategic and hands-on insights for builders, researchers, and engineering leaders. Notable strengths include rigorous technical depth, candid discussions about scale and safety, and a strong emphasis on open ecosystems and p... more

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Which podcasts are similar to Latent Space: The AI Engineer Podcast?

These podcasts share a similar audience with Latent Space: The AI Engineer Podcast:

1. No Priors: Artificial Intelligence | Technology | Startups
2. Training Data
3. Practical AI
4. Dwarkesh Podcast
5. Machine Learning Street Talk (MLST)

How many episodes of Latent Space: The AI Engineer Podcast are there?

Latent Space: The AI Engineer Podcast launched 4 years ago and published 221 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Latent Space: The AI Engineer Podcast?

Recent guests on Latent Space: The AI Engineer Podcast include:

1. Anima Anandkumar
2. Joon Sung Park
3. Neil Patil
4. Matt McPartlon
5. Philip Kiely
6. Ali Taha
7. Akshay Nathan
8. Eiso Kant

To view more recent guests and their details, simply upgrade your Rephonic account. You'll also get access to a typical guest profile to help you decide if the show is worth pitching.

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