JAMA Ophthalmology Author Interviews

JAMA Network

Ophthalmology

Diabetic Retinopathy

Diabetes

Age-Related Macular Degeneration

Semaglutide

Discrimination

Visual Acuity

Severe Spaceflight Associated Neuro-Ocular Syndrome

Clinical Trial

Bacterial Keratitis

Gender Inequality

Selective Laser Trabeculoplasty

Corneal Cross-Linking

Corticosteroids

Visual Impairment

Acute Infectious Conjunctivitis

Diversity

NASA

Stanford University

Retinopathy Of Prematurity

Interviews with authors of articles from JAMA Ophthalmology. JAMA Ophthalmology, published continuously since 1869, is an international, peer-reviewed ophthalmology and visual science journal. Covering research, science, & clinical practice in ophthalmology and vision science.

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Publishes	Monthly	Episodes	133	Founded	9 years ago
Number of Listeners		Categories	MedicineHealth & FitnessScience

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Latest Episodes

Diabetes Severity in Cornea Donors and 1-Year Outcomes in Recipients

Interview with Jonathan H. Lass, MD, author of Diabetes Severity in Cornea Donors and 1-Year Outcomes in Recipients in the Diabetes Endothelial Keratoplasty Study: A Secondary Analysis of a Randomized Clinical Trial. Hosted by Neil Bressler, MD. Rela... more

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Why Metrics Matter in Thyroid Eye Disease

Interview with Michael Kazim, MD, author of Why Metrics Matter in Thyroid Eye Disease: An Innovate TED Initiative. Hosted by Neil Bressler, MD. Related Content:

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Standardization of Retinal Vasculitis Terminology

Interview with Rupesh Agrawal, MMed, MD, and James T. Rosenbaum, MD, authors of Standardization of Retinal Vasculitis Terminology With Consensus Definitions From a Delphi Panel. Hosted by Neil Bressler, MD. Related Content:

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Nicotinamide and Primary Open-Angle Glaucoma in Ocular Hypertension

Interview with Iqbal Ike K. Ahmed, MD, and Jawad Muayad, MD, authors of Nicotinamide Supplementation and Primary Open-Angle Glaucoma in Patients With Ocular Hypertension. Hosted by Neil Bressler, MD. Related Content:

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Recent Guests

Michael Kazim

First author and key driver of the TED Innovate initiative

Harkness Eye Institute, Columbia University Medical Center

Episode: Why Metrics Matter in Thyroid Eye Disease

Rupesh Agrawal

Professor of Ophthalmology, corresponding author

National Healthcare Group I Institute in Singapore

Episode: Standardization of Retinal Vasculitis Terminology

James Rosenbaum

Chief of Ophthalmology Emeritus

Legacy Deversai Institute in Portland, Oregon

Episode: Standardization of Retinal Vasculitis Terminology

Iq Ahmed

Corresponding author; John A. Moran Eye Center, University of Utah

University of Utah

Episode: Nicotinamide and Primary Open-Angle Glaucoma in Ocular Hypertension

Jawad Muayad

First author; Bernice and Harvey Jones Eye Institute, University of Arkansas for Medical Sciences

University of Arkansas for Medical Sciences

Episode: Nicotinamide and Primary Open-Angle Glaucoma in Ocular Hypertension

Rishi Singh

Author of invited commentary; Chair of the Department of Ophthalmology at Massachusetts Eye and Ear Infirmary and Harvard Medical School

Massachusetts Eye and Ear Infirmary / Harvard Medical School

Episode: The Retina Clinic as a Window Into Systemic Vascular Health

Allison Summers

Associate professor of ophthalmology; first author of the Special Communication describing the tool

Oregon Health & Science University (OHSU)

Episode: Web-Based Amblyopia Decision Support Tool

Tiarnán Keenan

Corresponding author of the study

National Eye Institute, NIH

Episode: Geographic Atrophy Enlargement Rates in the AREDS2 Study

Alvin Liu

First author of the meta-analysis on prevalence and disparities of retinal conditions

Johns Hopkins University School of Medicine

Episode: Prevalence and Health Care Disparities of Retinal Conditions

Host

Neil Bressler

Editor-in-Chief of JAMA Ophthalmology; Host of JAMA Ophthalmology Author Interviews; frequently moderates conversations with leading researchers and clinicians in ophthalmology.

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Apple Podcasts	#20	Chile/Health & Fitness/Medicine
Apple Podcasts	#30	Taiwan/Health & Fitness/Medicine
Apple Podcasts	#110	Chile/Health & Fitness
Apple Podcasts	#138	Hong Kong/Health & Fitness/Medicine
Apple Podcasts	#153	Japan/Health & Fitness/Medicine
Apple Podcasts	#219	Argentina/Health & Fitness/Medicine
Apple Podcasts	#237	Belgium/Health & Fitness/Medicine
Apple Podcasts	#249	United Arab Emirates/Health & Fitness/Medicine

Talking Points

Recent interactions between the hosts and their guests.

Why Metrics Matter in Thyroid Eye Disease

Q: So your communication was talking a little bit about the clinical metrics that were used in research trials and what are those?

Metrics exist as individual measures (vision tests, proptosis, motility) and cumulative measures like CAS; however, CAS was not designed to determine activity vs. stability, which complicates evaluating new drugs and may limit its usefulness as a trial inclusion criterion.

Nicotinamide and Primary Open-Angle Glaucoma in Ocular Hypertension

Q: What safety considerations should clinicians keep in mind, and how do they address potential risks?

Liver injury risk emerges at higher doses (around 3 g/day) in global trials; thus, lower doses are generally safer, and any future trials must carefully monitor liver-related adverse events and establish safe, effective dosing regimens.

Nicotinamide and Primary Open-Angle Glaucoma in Ocular Hypertension

Q: What are the next steps before this could influence clinical practice?

The researchers advocate for a properly designed randomized controlled trial to determine dosing, safety, and efficacy, along with understanding interactions with genetics and real-world safety signals.

Nicotinamide and Primary Open-Angle Glaucoma in Ocular Hypertension

Q: What is the absolute risk reduction, and how does that translate into numbers for clinical decision-making?

Among those who started nicotinamide, about 3% converted to glaucoma compared with about 10% in those who did not, yielding roughly a 6% absolute risk reduction and roughly 1 in 18 individuals potentially spared from conversion in this dataset.

Nicotinamide and Primary Open-Angle Glaucoma in Ocular Hypertension

Q: What did the real-world data show about nicotinamide use and conversion to glaucoma, and how robust are those findings?

The analysis found a roughly two-thirds reduction in POAG diagnosis risk and reductions in related therapies, with results persisting across multiple sensitivity analyses, though the authors note possible healthy user bias and the need for randomized trials to confirm causation.

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Frequently Asked Questions About JAMA Ophthalmology Author Interviews

What is JAMA Ophthalmology Author Interviews about and what kind of topics does it cover?

A broad mix of clinically oriented Ophthalmology and vision science conversations focused on terminology standardization, real-world data applications, and the intersection of technology with eye care. Episodes frequently feature researchers and leading clinicians discussing consensus-building methods, imaging and diagnostic advances, and practical implications for diagnosis, treatment decisions, and research reporting. Notable threads include Delphi-driven terminology work for retinal vasculitis, real-world data analyses of glaucoma and nicotinamide, in-clinic measurements for systemic health indicators, web-based decision support tools for amblyopia, and AI or foundation-model discussions within ophthalmology. The show commonly highlights... more

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Which podcasts are similar to JAMA Ophthalmology Author Interviews?

These podcasts share a similar audience with JAMA Ophthalmology Author Interviews:

1. Ophthalmology Journal
2. Experts InSight
3. RETINA Journal Podcasts
4. New Retina Radio by Eyetube
5. The Retina Channel Podcast

How many episodes of JAMA Ophthalmology Author Interviews are there?

JAMA Ophthalmology Author Interviews launched 9 years ago and published 133 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on JAMA Ophthalmology Author Interviews?

Recent guests on JAMA Ophthalmology Author Interviews include:

1. Michael Kazim
2. Rupesh Agrawal
3. James Rosenbaum
4. Iq Ahmed
5. Jawad Muayad
6. Rishi Singh
7. Allison Summers
8. Tiarnán Keenan

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