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Artwork for from Dreamers to Disruptors

from Dreamers to Disruptors

Medidata
Clinical Trials
Artificial Intelligence
Medidata
7wire Ventures
External Control Arms
Real-World Evidence
AI In Clinical Trials
Click Therapeutics
Patient Centricity
Data Tokenization
Digital Medicine Society
Every Cure
Livongo
Pancreatic Cancer
Regulators (MHRA, FDA)
Castleman Disease
Health Policy
Decentralized Trials
Healthcare
Data In Healthcare

This is a call to the world's visionaries who made waves. The ones who gave themselves the green light to turn bold dreams into disruptive realities and shake up the status quo. Hear straight from industry leaders across tech, healthcare, and life sciences as they share their stories and innovations with us. This is from Dreamers to Disruptors, a Medidata podcast.

PublishesMonthlyEpisodes14Foundeda year ago
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TechnologyScienceLife Sciences

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Artwork for from Dreamers to Disruptors

Latest Episodes

New technologies have always driven advances in clinical research, and that's still true today. The Covid pandemic rapidly accelerated the adoption of decentralized trials, powered by emerging health tech, but in less dramatic times, life sciences mu... more

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At its heart, Medidata NEXT is a conversation where leading experts in clinical research come together in open dialogue. Representing the biggest names in healthcare and life sciences from around the world, they explore industry challenges and share ... more

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External Control Arms are a powerful clinical research tool, harnessing cutting-edge tech to fill gaps in clinical data and accelerate trials when patients' lives are on the line. They're particularly valuable for cancer research, where patients can ... more

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NEXT New York is our flagship event, bringing together the world's leading life sciences companies and thinkers to envision a transformative future for healthcare that challenges our preconceptions of what's possible in clinical trials.

This specia... more

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Recent Guests

Nitish Mittal
Executive at Everest Group
Everest Group
Episode: Medidata NEXT London 2026 LIVE
Krzysztof Wróblewski
Executive at AstraZeneca
AstraZeneca
Episode: Medidata NEXT London 2026 LIVE
Anthony Costello
CEO at Medidata
Medidata
Episode: Medidata NEXT London 2026 LIVE
Chris Standley
VP of Data Governance
Worldwide Clinical Trials
Episode: Medidata NEXT London 2026 LIVE
Robyn Orie
VP of Clinical Data Management
Caidya
Episode: Medidata NEXT London 2026 LIVE
Casey Kendrew
COO
EMS Healthcare
Episode: Medidata NEXT London 2026 LIVE
Amandeep Heer
Board Member, Lakeside Healthcare and Site Insights
Lakeside Healthcare
Episode: Medidata NEXT London 2026 LIVE
Jeff Allen
President and CEO of Friends of Cancer Research
Friends of Cancer Research
Episode: Fighting Cancer with External Control Arms: Friends of Cancer Research's Jeff Allen
Ruthie Davi
Senior Vice President of Statistics and Regulatory Science Innovation at Medidata
Medidata
Episode: Fighting Cancer with External Control Arms: Friends of Cancer Research's Jeff Allen

Hosts

Lisa Moneymaker
Chief Strategy Officer at Medidata, Medidata
Anthony Costello
Host of the podcast; has led conversations on AI strategy, platform integration, and industry-wide deployment within Medidata ecosystem

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Talking Points

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Fighting Cancer with External Control Arms: Friends of Cancer Research's Jeff Allen
Q: How does this approach affect future clinical trials and regulatory discussions?
If external controls can be validated in specific indications, they can augment trials, reduce the number of patients exposed to ineffective standard therapies, speed up results, and provide a framework for early and ongoing regulatory dialogue to set expectations and precedents.
Fighting Cancer with External Control Arms: Friends of Cancer Research's Jeff Allen
Q: What were the key components of the collaboration between Medidata and Friends of Cancer Research?
The collaboration integrated data from multiple sources, rigorous study design, protocol development, regulatory engagement with the FDA, and a shared aim to validate external controls in a real-world setting, starting with pancreatic cancer and expanding to other indications.
Fighting Cancer with External Control Arms: Friends of Cancer Research's Jeff Allen
Q: What is an external control arm and why is it needed in certain cancers like pancreatic cancer?
An external control arm uses historical or external data to replicate the conditions of a traditional control group, allowing less reliance on randomization when the standard of care is undesirable or when ethical concerns make a randomized control difficult; it requires careful balancing of known covariates and high-quality data.
AI Ethics, Patient Recruitment, and a New Vision for Clinical Data: Arnaub Chatterjee
Q: How do you address consent and patient trust in this data-centric approach?
We emphasize patient-friendly interfaces and early, opt-in consent that ties in with health record portals and EMR data, ensuring patients understand how their data will be used and can participate in trials without compromising trust or recruitment.
AI Ethics, Patient Recruitment, and a New Vision for Clinical Data: Arnaub Chatterjee
Q: What would you identify as the core dream driving your work in AI and data for clinical trials?
The core dream is to redesign drug development by starting with long-tail evidence and linking data across a patient's entire lifecycle, from pretrial to post-market, so trials are faster, safer, and more broadly representative.

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Frequently Asked Questions About from Dreamers to Disruptors

What is from Dreamers to Disruptors about and what kind of topics does it cover?

This show consistently features leaders from healthcare technology, life sciences, and digital health who discuss how AI, data governance, and new trial models are transforming clinical research. Episodes frequently explore AI-integration challenges, regulatory collaboration, data quality and governance, patient-centric trial design, and innovative business models that align providers, payers, and patients. A notable throughline is the emphasis on practical implementation—how to operationalize AI, how to enable multi-vendor data ecosystems, and how digital therapeutics and repurposing strategies can accelerate outcomes. The format tends to blend strategic storytelling with concrete examples from industry leaders, regulators, and policy-focu... more

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from Dreamers to Disruptors launched a year ago and published 14 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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Recent guests on from Dreamers to Disruptors include:

1. Nitish Mittal
2. Krzysztof Wróblewski
3. Anthony Costello
4. Chris Standley
5. Robyn Orie
6. Casey Kendrew
7. Amandeep Heer
8. Jeff Allen

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