
Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical relevance—one base at a time. Powered by AI, Base by Base offers a new way to learn on the go. Special thanks to authors who publish under CC BY 4.0, maki... more
| Publishes | Daily | Episodes | 250 | Founded | 9 months ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Life SciencesScienceMedicineHealth & Fitness | |||

️ Episode 250: CIP2A–TOPBP1: Mitotic repair via MiDAS and MMEJ
In this episode of PaperCast Base by Base, we explore This study shows the CIP2A-TOPBP1 complex coordinates two mitotic double-strand break repair pathways, MiDAS and MMEJ, by recruitin... more
️ Episode 249: PCM1 links centrosome asymmetry to endosome dynamics
In this episode of PaperCast Base by Base, we explore In developing neural progenitors PCM1 localizes to the mother centrosome and to Notch ligand-containing endosomes, promoting P... more
️ Episode 248: Disruption of PIKfyve triggers lysosomal repair and mitochondrial adaptation
In this episode of PaperCast Base by Base, we explore Disruption of the PIKfyve/Fig4/Vac14 complex drives ULK1-dependent trafficking of PI4KIIα and ATG9A to... more
️ Episode 247: Genome graphs reveal structural variation in M. tuberculosis
In this episode of PaperCast Base by Base, we explore Long-read assemblies and a pangenome reference graph uncover widespread structural variants that shape Mycobacterium t... more
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
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Apple Podcasts | #137 |
Recent interactions between the hosts and their guests.
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Exploring the intricacies of genetics and genomics, this podcast provides insightful discussions on gene-disease associations, protein structure, and the implications of cutting-edge research in exome and genome sequencing. Each episode meticulously breaks down prominent studies, linking complex scientific concepts to their clinical relevance and practical applications. With a strong focus on recent advancements, the content is likely to resonate with listeners interested in how genetic factors play a crucial role in health and disease. The educational format is conducive for listeners eager to expand their knowledge on genetic science while on the move, making advanced topics accessible to a broad audience.
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Base by Base launched 9 months ago and published 250 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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Recent guests on Base by Base include:
1. Research Team from Duke University
2. Tianxin Zeng
3. Alan J. Aw
4. Marcus W. Feldman
5. Anna Axakova
6. Megan Ding
7. Jacques Fellay
8. Dr. Lucas da Silva
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