Base by Base
Gustavo BarraBase by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical relevance—one base at a time. Powered by AI, Base by Base offers a new way to learn on the go. Special thanks to authors who publish under CC BY 4.0, maki... more
| Publishes | Daily | Episodes | 388 | Founded | a year ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | MedicineScienceHealth & FitnessLife Sciences | |||
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Latest Episodes
Peeters MKR et al., Proceedings of the National Academy of Sciences (PNAS) - A perspective outlining how genome doubling (polyploidy) reshapes genomes, phenotypes, and ecological interactions and how its immediate effects can be harnessed across agri... more
Sarabia Olivera L et al., PNAS - A perspective that surveys how diverse stresses trigger whole‑genome doubling (polyploidy) across fungi, plants, and animals, outlines common cell‑cycle mechanisms that produce polyploid cells, and evaluates the benef... more
Haycocks JRJ et al., PNAS - This episode examines the discovery of CisR, a small RNA produced from the 3’UTR of prtV in Vibrio cholerae, which posttranscriptionally represses the CTXϕ-encoded cep mRNA via Hfq-mediated base-pairing. CisR accumulation ... more
Koprulu M et al., Cell - A 38-cohort proteogenomic meta-analysis of up to 78,664 people maps fine‑mapped protein quantitative trait loci (pQTLs) across 1,116 circulating proteins, uses machine learning to assign trans effector genes, and triangulates... more
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Apple Podcasts | #238 |  United Kingdom/Science/Life Sciences |
Apple Podcasts | #99 |  Germany/Science/Life Sciences |
Apple Podcasts | #67 |  Singapore/Science/Life Sciences |
Apple Podcasts | #84 |  South Africa/Science/Life Sciences |
Apple Podcasts | #86 |  China/Science/Life Sciences |
Apple Podcasts | #121 |  Sweden/Science/Life Sciences |
Apple Podcasts | #246 |  Japan/Science/Life Sciences |
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Frequently Asked Questions About Base by Base
What is Base by Base about and what kind of topics does it cover?
This show centers on advances in genetics and genomics, with a strong emphasis on how new studies translate to clinical understanding. Episodes commonly unpack topics like biobank biases, polygenic risk scores, transcriptional and regulatory mechanisms, genome-wide association methods, and the practicalities of implementing genomic insights in healthcare. Across installments, the hosts tend to connect methodological nuances to real-world implications—ranging from diagnostic yield and disease risk prediction to ethical considerations and health equity—often highlighting innovative analytic techniques (e.g., weighting schemes, NLP in clinical data, and population-specific reference resources) and the challenges of translating cutting-edge res... more
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Which podcasts are similar to Base by Base?
These podcasts share a similar audience with Base by Base:
1. The Proof with Simon Hill
2. Mind Pump: Raw Fitness Truth
3. The Nation Podcasts
4. Ones and Tooze
5. The Mel Robbins Podcast
How many episodes of Base by Base are there?
Base by Base launched a year ago and published 388 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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What guests have appeared on Base by Base?
Recent guests on Base by Base include:
1. Matu Mantecon
2. Agnes Roetig
3. Jirko Kuhnisch
4. Kaneco Weaver
5. Ruby White
6. Christophe Pellefigues
7. Franca Ronchese
8. Olivier Lamiable
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