Base by Base
Gustavo BarraBase by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical relevance—one base at a time. Powered by AI, Base by Base offers a new way to learn on the go. Special thanks to authors who publish under CC BY 4.0, maki... more
| Publishes | Daily | Episodes | 420 | Founded | a year ago |
|---|---|---|---|---|---|
| Number of Listeners | Categories | Life SciencesScienceMedicineHealth & Fitness | |||
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Latest Episodes
Felici B et al., Cell Genomics - A concise review of how post-GWAS methods are being used to move from statistical associations to translational insights by integrating drug-target prioritization, single-cell resolution of regulatory mechanisms, and ... more
Garcia-Salinas OI et al., The American Journal of Human Genetics - Garcia-Salinas et al. develop a bioinformatic pipeline to recover early parental postzygotic mutations (PZMs) from standard-depth (~30×) trio WGS and apply it to 12,015 rare-disease t... more
Kapoor RR et al., PNAS - A systematic screen of 319 arthropod genomes reveals genes formed by in‑frame fusion of horizontally transferred nonmetazoan sequences with endogenous metazoan regions. Many of these HGT-chimeras are transcribed, conserved, a... more
PNAS - This episode breaks down a PNAS study that identifies a druggable pocket in the ERG transcription factor PNT domain and describes PBITE-1, a small-molecule probe that binds this pocket to inhibit ERG-driven prostate cancer models. Key terms: E... more
Recent Guests
Chart Rankings
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #189 |  United States/Science/Life Sciences |
Apple Podcasts | #112 |  Australia/Science/Life Sciences |
Apple Podcasts | #161 |  Germany/Science/Life Sciences |
Apple Podcasts | #23 |  Austria/Science/Life Sciences |
Apple Podcasts | #117 |  China/Science/Life Sciences |
Apple Podcasts | #119 |  Singapore/Science/Life Sciences |
Apple Podcasts | #119 |  South Africa/Science/Life Sciences |
Apple Podcasts | #123 |  Brazil/Science/Life Sciences |
Apple Podcasts | #160 |  Belgium/Science/Life Sciences |
Apple Podcasts | #187 |  Sweden/Science/Life Sciences |
Talking Points
Recent interactions between the hosts and their guests.
Audience Metrics
Listeners, social reach, demographics and more for this podcast.
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Frequently Asked Questions About Base by Base
What is Base by Base about and what kind of topics does it cover?
A deep dive into cutting-edge genetics and genomics research, with episodes covering innovative techniques for mapping gene expression in tissues, strategies to map drug resistance in cancer, and advances in RNA-targeting CRISPR systems. Discussions often center on how new open-access studies can translate to clinical practice, from multiomic spatial mapping and immunoproteasome biology to RNA-targeting diagnostics and genetic-code malleability. A notable throughline is the emphasis on practical applications—proactive cancer strategies, diagnostic innovations, and the potential for personalized medicine—coupled with a strong openness ethos driven by CC BY 4.0 licensing. Listeners can expect rigorous explanations of experimental methods, tra... more
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Which podcasts are similar to Base by Base?
These podcasts share a similar audience with Base by Base:
1. Knife Down
How many episodes of Base by Base are there?
Base by Base launched a year ago and published 420 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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What guests have appeared on Base by Base?
Recent guests on Base by Base include:
1. Hunter Gaudio
2. Andrew Bliss
3. Matu Mantecon
4. Agnes Roetig
5. Jirko Kuhnisch
6. Kaneco Weaver
7. Ruby White
8. Christophe Pellefigues
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