The Peripheral Nerve Podcast

Peripheral Nerve Society (PNS)

Leprosy

Chemotherapy Induced Peripheral Neuropathy

Chemotherapy-Induced Peripheral Neuropathy

Schwann Cells

Leprosy Neuropathy

Oxaliplatin

Biomarkers

Rio De Janeiro, Brazil

Mumbai, India

Brazil

Nerve Involvement

Social Determinants Of Health

Mycobacterium Leprae

Demyelination

Regeneration and Plasticity

Nerve Biopsy

Regeneration

Diagnostic Tools For Leprosy

Relapse and Treatment Failure In Leprosy

Nerve Conduction Studies

The Peripheral Nerve Podcast is the official podcast of the Peripheral Nerve Society (PNS). In each multi-episode series, we fully explore a topic, bringing in expert guests from around the world to share their insights, illuminate the subject and provide practical knowledge for clinicians and basic scientists. As an international organization, we strive to provide insight into topics from a globa... more

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Publishes	Monthly	Episodes	13	Founded	a year ago
Number of Listeners		Categories	Health & FitnessScienceMedicine

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Latest Episodes

Clinical Translation and Symptom Management in Chemotherapy Induced Peripheral Neuropathy

Chemotherapy-induced peripheral neuropathy (CIPN) remains one of the most common and challenging complications of cancer treatment. While significant progress has been made in understanding the condition, measuring treatment success and developing ef... more

7 Jul 2026 • 14 min

Precision Medicine: Biomarkers and Risk Prediction in Chemotherapy Induced Peripheral Neuropathy

Why do some patients develop severe chemotherapy-induced peripheral neuropathy (CIPN) while others receiving the same treatment experience little or no nerve damage?

In this episode, Drs. Paola Alberti and Susanna Park welcome Professor Roser Velas... more

9 Jun 2026 • 24 min

Neurotoxicity and Chemotherapy - An Oncology Perspective

In this episode of the Peripheral Nerve Podcast, hosts Susanna Park and Paola Alberti are joined by Maryam Lustberg to explore the real-world impact of chemotherapy-induced peripheral neuropathy (CIPN). Together, they examine why CIPN remains such a ... more

12 May 2026 • 16 min

Cellular and Molecular Mechanisms of Chemotherapy Induced Peripheral Neuropathy Pathophysiology

In this episode of the Peripheral Nerve Podcast, hosts Dr. Paola Alberti (University of Milano-Bicocca, Italy) and Professor Susanna Park (University of Sydney, Australia) are joined by Professor Guido Cavaletti (University of Milano-Bicocca, Italy),... more

14 Apr 2026 • 15 min

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American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM)AANEM

Recent Guests

Jennifer Gewandter

Associate Professor; leading clinical researcher in pain neuropathy and clinical trial methodology

University of Rochester

Episode: Clinical Translation and Symptom Management in Chemotherapy Induced Peripheral Neuropathy

Roser Velasco

Neurologist and principal investigator at the Neuro-Oncology Group of the Catalan Institute of Oncology

Catalan Institute of Oncology, Bellevue University Hospital, Barcelona; Adjunct Professor at Universitat Autònoma de Barcelona

Episode: Precision Medicine: Biomarkers and Risk Prediction in Chemotherapy Induced Peripheral Neuropathy

Maryam Lustberg

Professor of Breast Medical Oncology and Director of the Center for Breast Cancer at Smilow Cancer Hospital

Yale Cancer Center

Episode: Neurotoxicity and Chemotherapy - An Oncology Perspective

Guido Cavaletti

Professor and global CIPN leader, contributor to mechanistic CIPN research

University of Milan

Episode: Cellular and Molecular Mechanisms of Chemotherapy Induced Peripheral Neuropathy Pathophysiology

David Scholar

Professor, retired director of National Health and Disease Program, USA

National Health and Disease Program, USA

Episode: Treatment, Prognosis, Prevention

Wim Bambracheal

Dr. Wim Bambracheal, former medical director in NRI, secretary of International Leopard Association

International Leopard Association

Episode: Treatment, Prognosis, Prevention

Marcelo Nogueira-Barbosa

Professor of Radiology and expert in high-resolution nerve ultrasound

Universidade de São Paulo, Ribeirão Preto

Episode: Pathology and imaging methods in leprosy neuropathy

Diogo Fernandes

Professor of Neurology, Neurologist and Clinical Neurophysiologist

Universidade Federal de Uberlândia; National Reference Center for Sanitary Dermatology and Hansenology

Episode: Pathology and imaging methods in leprosy neuropathy

Pedro Tomaselli

Professor of Neurology

University of São Paulo, Ribeirão Preto

Episode: Electrophysiology, Schwann Cell Biology, and the Neurophysiological Mechanisms of Leprosy Neuropathy

Hosts

Camila Pupe

Host of The Peripheral Nerve Podcast

Wilson Marques Jr.

Co-host introducing episode and guiding discussion/Co-host of The Peripheral Nerve Podcast

Chart Rankings

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Apple Podcasts	#171	Argentina/Health & Fitness/Medicine
Apple Podcasts	#190	Saudi Arabia/Health & Fitness/Medicine

Talking Points

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Clinical Translation and Symptom Management in Chemotherapy Induced Peripheral Neuropathy

Q: What opportunities do you think are there for clinical translation of these research findings in the short term to improve management of CIPN?

In the short term, improving patient education about available treatments like duloxetine and ensuring clinicians offer them, along with better symptom tracking and nurse-led follow-up to trigger timely interventions, can enhance management. Biomarkers may aid earlier-stage decisions, but the primary clinical outcomes should remain patient-reported for symptomatic trials.

Clinical Translation and Symptom Management in Chemotherapy Induced Peripheral Neuropathy

Q: I was wondering if you could provide us with a brief overview of outcome measure which quantifies CIPN and discuss how we define a clinically meaningful change in CIPN severity and if there are any methodological pitfalls you would like to highlight for us.

There are multiple types of outcome measures, including patient-reported symptoms and clinician-rated signs; measures like CIPN20, FACT-Taxane, and EORTC-CIPN20 tend to be more reproducible, while CTCIE has both patient and clinician versions but may be less specific. Clinically meaningful change is often understood in terms of grade shifts (e.g., reduction in grade 3 neuropathy), and continuous measures require careful interpretation; alignment of the measure with the expected intervention is crucial.

A Spectrum of Challenges: Understanding Classification and Immunology in Leprosy

Q: What should young clinicians focus on to make an impact in leprosy care today?

Develop a strong skill set in neurological assessment, including palpation of nerves, thermal and pain sensitivity tests, dysautonomia assessments, and ultrasound when available; pursue training that blends clinical acumen with awareness of social determinants and field-based surveillance to improve early diagnosis and patient outcomes.

A Spectrum of Challenges: Understanding Classification and Immunology in Leprosy

Q: What are the main limitations of the current operational classifications, and how could they be improved?

The WHO classification is simplistic and skin-lesion-centric, often neglecting nerves; this leads to misclassification, especially in cases with neural symptoms. Digital tools and high-frequency ultrasound show nerve involvement in determinate forms, suggesting a more nuanced system is needed that includes neural criteria and social factors.

A Spectrum of Challenges: Understanding Classification and Immunology in Leprosy

Q: Do hypersensitivity tests or markers currently help differentiate reactions from relapses, and how are these managed clinically?

Differentiation remains primarily clinical; most patients are managed based on observed activity and response to steroids, with improvements in neural signs after MDT suggesting better outcomes than earlier epidemiological indicators. Relapses may be indicated by rising anti-PGL-1 titers at multibacillary sites, but overall immunologic tests are not decisive for diagnosis.

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Frequently Asked Questions About The Peripheral Nerve Podcast

What is The Peripheral Nerve Podcast about and what kind of topics does it cover?

The show centers on neurological diseases affecting peripheral nerves, with a strong emphasis on leprosy neuropathy and chemotherapy-induced peripheral neuropathy (CIPN). Episodes commonly feature international researchers and clinicians discussing mechanisms, diagnostics, and patient-centered management, often weaving together imaging, electrophysiology, pathology, and public health perspectives. A recurring strength is bringing together basic science and clinical practice from regions with high leprosy burden, alongside translational insights for cancer-related neuropathies, rehabilitation, and patient-reported outcomes. The format tends to highlight multidisciplinary collaboration, practical workflows, and emerging biomarkers or imaging ... more

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Which podcasts are similar to The Peripheral Nerve Podcast?

These podcasts share a similar audience with The Peripheral Nerve Podcast:

1. American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM)

How many episodes of The Peripheral Nerve Podcast are there?

The Peripheral Nerve Podcast launched a year ago and published 13 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Peripheral Nerve Podcast?

Recent guests on The Peripheral Nerve Podcast include:

1. Jennifer Gewandter
2. Roser Velasco
3. Maryam Lustberg
4. Guido Cavaletti
5. David Scholar
6. Wim Bambracheal
7. Marcelo Nogueira-Barbosa
8. Diogo Fernandes

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