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Artwork for The Lancet Gastroenterology & Hepatology in conversation with

The Lancet Gastroenterology & Hepatology in conversation with

The Lancet Group
Inflammatory Bowel Disease
Colorectal Cancer
Crohn's Disease
Hepatitis B
Low FODMAP Diet
Car-Ibs Trial
Pharmacological Treatments
Low Carbohydrate Diet
Irritable Bowel Syndrome
Colonoscopy
Intestinal Ultrasound
ASCOLT Trial
Decompensated Cirrhosis
Acute Kidney Injury
Viral Hepatitis Elimination
Hepsinet
Sub-Saharan Africa
Profile Trial
Biomarker
Symptom Management

Hugh Thomas, Deputy Editor at The Lancet Gastroenterology & Hepatology, in conversation with the journal’s authors, explores their latest research and its impact on people’s health, healthcare, and health policy.

A monthly audio companion to the journal, this podcast covers a broad range of topics, from predicting clinical outcomes in NAFLD to immunosuppressant withdrawal in patients with Crohn’s ... more

PublishesInfrequentlyEpisodes87Founded5 years ago
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Life SciencesHealth & FitnessMedicineScience

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Artwork for The Lancet Gastroenterology & Hepatology in conversation with

Latest Episodes

Can a multi-metabolite blood test improve early pancreatic cancer detection? We spoke to Julia Mayerle about the METAPAC study, which sought to validate the ability of plasma metabolic signatures to find resectable tumors and reduce unnecessary invas... more

How does acute kidney injury presentation and management differ globally for patients hospitalised with cirrhosis? 

We spoke to Salvatore Piano, corresponding author of the landmark International Club of Ascites GLOBAL AKI study, about new data on r... more

John Chia discusses the results of the ASCOLT trial, which explored the effect of aspirin after completion of standard adjuvant therapy for patients with colorectal cancer.

Read the full article:

www.thelancet.com/journals/langas/article/PI... more

Hannes Hagström discusses a study investigating the feasibility of screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes.

Read the full article:

www.thelancet.com/journals/langas/article/PIIS2468-1253... more

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Recent Guests

Dr. Salvatore Piano
Associate Professor of Internal Medicine and Consultant Hepatologist
University and Hospital of Padua, Italy
Episode: Salvatore Piano on the global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis
John Chia
Consultant medical oncologist at Curie Oncology; formerly chief of gynecology oncology service at the National Cancer Centre Singapore
Curie Oncology
Episode: John Chia on the ASCOLT trial of adjuvant aspirin for colorectal cancer
Professor Hannes Hagström
Consultant in Hepatology at the Karolinska University Hospital and professor with a research focus on liver disease epidemiology.
Karolinska Institute
Episode: Hannes Hagström on screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes
Dr. Cathy Lu
Associate Professor at the University of Calgary and first author of the consensus statement.
University of Calgary
Episode: Cathy Lu on intestinal ultrasound for assessing and monitoring Crohn's disease small bowel strictures
Dr. Peter De Cruz
Director of the IBD Service at the Austin Hospital and a Senior Lecturer at the University of Melbourne
Austin Hospital, University of Melbourne
Episode: Peter De Cruz on the PREDICT-UC trial of intensified versus standard dose infliximab for steroid-refractory acute severe ulcerative colitis
Professor Arndt Vogel
Clinician scientist and full professor at the University of Toronto, Canada, leading research in liver cancer.
University of Toronto
Episode: Arndt Vogel on the NALIRICC trial of nanoliposomal irinotecan in pretreated advanced biliary tract cancer
Professor Nancy Baxter
Professor at the University of Melbourne and a Senior Adjunct Scientist at the Institute for Clinical Sciences in Toronto; a colorectal surgeon and health services researcher focusing on population-based health data.
University of Melbourne, Institute for Clinical Sciences, Toronto
Episode: Nancy Baxter on the duration of colorectal cancer risk reduction with a complete colonoscopy
Sanna Nybacka
Dietitian and postdoctoral researcher at the Department of Molecular and Clinical Medicine
University of Gothenburg
Episode: Sanna Nybacka and Magnus Simrén on a trial of low FODMAP diets versus low carbohydrate diets in IBS
Magnus Simrén
Professor of cancer and neurology and senior consultant
University of Gothenburg
Episode: Sanna Nybacka and Magnus Simrén on a trial of low FODMAP diets versus low carbohydrate diets in IBS

Host

Hugh Thomas
Deputy Editor at The Lancet Gastroenterology & Hepatology

Chart Rankings

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Talking Points

Recent interactions between the hosts and their guests.

Salvatore Piano on the global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis
Q: Can you elaborate on the finding regarding the association of lower universal health coverage with mortality?
It underscores the need for equitable healthcare access as a determinant of survival in AKI patients with cirrhosis.
Salvatore Piano on the global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis
Q: What factors are underlying these regional variations and how do you think they're impacting patient outcomes?
Local regulatory landscapes, cost, and accessibility of treatments contribute to regional management differences which likely impact patient outcomes.
Salvatore Piano on the global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis
Q: What led your team to undertake this global assessment with such a broad range of collaborators?
To provide a global perspective on the prevalence and management of AKI in decompensated cirrhosis, given its high susceptibility and life-threatening nature.
Arndt Vogel on the NALIRICC trial of nanoliposomal irinotecan in pretreated advanced biliary tract cancer
Q: What are the next steps in research for biliary tract cancer according to Professor Vogel?
The focus will likely shift to combinations of therapies and better understanding of the biomarkers to improve treatment efficacy for biliary tract cancer.
Arndt Vogel on the NALIRICC trial of nanoliposomal irinotecan in pretreated advanced biliary tract cancer
Q: What insights can be derived from the comparison of Naliric results to other trials like NIFTY?
There are significant differences in outcomes that may be attributed to study design, demographics, and possibly drug metabolism variations between populations.

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What is This Podcast about and what kind of topics does it cover?

This series features in-depth discussions on pivotal research and breakthroughs in gastroenterology and hepatology, focusing on their implications for healthcare and health policy. Episodes cover diverse topics, from advanced liver disease management strategies to innovations in inflammatory bowel disease treatment and antibiotic resistance. Noteworthy is a strong emphasis on both clinical practice and patient-centered approaches, aiming to bridge the gap between research findings and real-world applications in healthcare settings.

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These podcasts share a similar audience with this podcast:

1. American Journal of Gastroenterology Author Podcasts
2. Gastroenterology & Endoscopy
3. JAMA Editors' Summary

How many episodes of this podcast are there?

this podcast launched 5 years ago and published 87 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on this podcast?

Recent guests on this podcast include:

1. Dr. Salvatore Piano
2. John Chia
3. Professor Hannes Hagström
4. Dr. Cathy Lu
5. Dr. Peter De Cruz
6. Professor Arndt Vogel
7. Professor Nancy Baxter
8. Sanna Nybacka

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