糖尿病科學前線
Ander尿病科學前線是一個專門針對糖尿病相關研究的深度討論節目。我們每週邀請頂尖的醫學專家、研究人員和臨床醫生，深入探討糖尿病最新的科學發現、治療趨勢及相關公共衛生議題。每一集都會涵蓋最新的學術期刊文章、技術創新，以及如何在臨床實踐中應用這些突破，幫助聽眾理解糖尿病管理的未來趨勢。不論你是醫療專業人士還是關心糖尿病患者，這裡都有深入且具啟發性的內容供你學習。
| Publishes | Weekly | Episodes | 21 | Founded | a year ago |
|---|---|---|---|---|---|
| Language |  Korean | Categories | MedicineHealth & Fitness | ||
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在這一集中，我們將深入探討矽谷思想家 Naval Ravikant 關於「致富」的核心理念。Naval 提出，致富並非依靠運氣，而是透過長期累積、正確思維與槓桿應用。他強調要建立「專屬於你的知識與技能」，並懂得如何運用科技、資本與人脈，讓成果能在時間中不斷複利增長。與其追求短期報酬或盲目模仿他人，不如專注培養不可取代的價值與獨特見解。致富是一種心態轉換：從時間換取金錢，轉向創造可以無限複製的價值。Naval 也提醒，財富的意義不僅在於金錢本身，而是能帶來更多自由、選擇權與心靈上的滿足。本集將帶你... more
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MODY 與妊娠糖尿病的鑑別
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遺傳風險與胎兒健康
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青年糖尿病女性的生育照護
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家族性糖尿病的臨床案例探討
MODY 是一種單基因突變導致的糖尿病，具有以下特點：
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通常於 25 歲前發病
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家族性遺傳（常染色體顯性）
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不依賴胰島素、胰島素分泌保留
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不伴有胰島素抗性或自體免疫指標
| 分型 | 基因 | 臨床特徵 | 治療反應 |
| ------ | ----- | -------------- | ---------- |
| MODY 1 | HNF4A | 青年起病、口服藥反應佳 | 對磺醯脲類藥物極敏感 |
| MODY 2 | GCK |... more
多囊性卵巢綜合症 (PCOS) 的代謝問題，以及胰高血糖素樣肽-1 受體激動劑 (GLP-1 RAs) 和 二肽基肽酶-4 (DPP-4) 抑制劑等藥物在治療相關症狀方面的潛在益處。多囊性卵巢綜合症患者常伴有肥胖、胰島素抵抗和高雄激素血症，這些藥物旨在通過減輕體重、改善胰島素敏感性和調節激素水平來解決這些問題。此外，資料還提及了替西帕肽 (Tirzepatide)，一種新的 GLP-1/GIP 雙重受體激動劑，被視為治療肥胖型多囊性卵巢綜合症的未來潛力療法。研究同時討論了這些藥物可能對某些皮膚病... more
本週《生活升級Hacks》邀請到收納界的超人氣達人──美琪老師，帶大家破解整理的心理障礙，從「改變觀念」到「實戰技巧」，一步步帶領整理新手踏出第一步。你會發現，整理不再是苦差事，而是一場找回生活掌控權、打造理想空間的旅程。從15分鐘整理法、暫存區妙用，到「物歸原位」的長效維持術，無論你是懶癌末期還是收納苦手，都能找到屬於自己的整理節奏。讓美琪老師陪你一起，從小小角落開始，迎向清爽自在的新生活！
本集將深入解析停經後女性高雄激素血症的臨床表現與鑑別診斷重點。內容涵蓋多毛症的分級與初步評估、LH/FSH比值的臨床意義、卵巢增生症的病理機轉與影像診斷、以及如何判斷卵巢或腎上腺來源的雄激素分泌腫瘤。我們也會討論 PCOS 在停經後的持續影響，以及高雄激素的治療策略，包括抗雄激素療法與手術考量。適合臨床醫師、內分泌學者及對婦女內分泌有興趣的聽眾。
SGLT2 抑制劑是一類能促進尿糖排出、改善血糖與心腎保護的藥物。然而在圍手術期，這類藥物可能導致一項潛在嚴重但不常見的併發症：優糖性酮酸中毒（euglycemic diabetic ketoacidosis, eDKA）。
在禁食、感染、脫水或手術應激的情境下，病人體內胰島素需求增加，而 SGLT2 抑制劑仍促使尿糖排出，進一步降低血糖水平，掩蓋傳統酮酸中毒的高血糖特徵，導致延遲診斷。
圍手術期停藥建議如下：
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輕度或中型手術：建議手術前至少 3 天停藥（72 小時）
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SGLT2 抑制劑因其心腎保護效益在接受手術的第二型糖尿病病人中日益常見，但藥物機轉會提升酮體生成並降低血糖，使「無高血糖酮酸中毒」成為重要圍手術風險。最新美國糖尿病學會 2025 標準及多數專家共識建議，選擇性停藥三天（72 小時）可明顯降低術後 eDKA 發生率，若預期術式大、禁食時間長或病人伴隨腎功能不全，應延長至四天。
機轉上，SGLT2 抑制劑透過抑制腎近曲小管回收葡萄糖，術中禁食與壓力賀爾蒙進一步促進脂肪酸氧化與酮體累積；胰島素分泌相對不足時，即使血糖低於 250 mg/dL 仍可... more
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