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Artwork for Talk Python To Me

Talk Python To Me

Michael Kennedy
Python
Data Science
Machine Learning
Django
Fastapi
Pydantic
Web Development
Large Language Models
Pandas
Open Source
Flask
Rust
Marimo
Cpython
Jupyter Notebooks
Natural Language Processing
Cloud Computing
Data Analysis
Open Source Software
Programming

Talk Python to Me is a weekly podcast for Python developers, data scientists, and AI builders, hosted by developer and entrepreneur Michael Kennedy. We dive deep into the packages, tools, and people shaping Python, from web development and data science to AI and LLMs. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from its leaders. And if you've been Pyt... more

PublishesWeeklyEpisodes567Founded12 years ago
Number of ListenersCategory
Technology

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Artwork for Talk Python To Me

Latest Episodes

Where does your Python code actually run? A server in Virginia? A container in Frankfurt? Pyodide put Python into the browser. Cloudflare put the browser into the server. Combine the two and you get Python Workers, now generally available. My guests ... more

YouTube

The most popular Python project you've probably never heard of has 252,000 GitHub stars and merged over 1,800 pull requests in a single week. It's Hermes, a self-hosted AI agent you program just by talking to it. And it never clocks out. It runs 24/7... more

YouTube

Which of your Python tools would you still pick if you started fresh today? For a long time, the answer was easy. The stack felt settled. AI has reopened almost every one of those choices. Some tools got faster. Others got replaced outright. On this ... more

YouTube

Do you know what's actually slow in your Python app? Or are you guessing? Until now, profiling Python meant a tracing profiler that made your code 2 to 3 times slower. Or a third-party tool that broke with every new release. Python 3.15 fixes that. I... more

YouTube

Key Facts

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Contact Information
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Find out how many people listen to this podcast per episode and each month.

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Recent Guests

Hood Chatham
Mathematician and Pyodide maintainer working on Python Workers
Cloudflare
Episode: #568: Cloudflare Python Workers
Gyeongjae Choi
Pyodide maintainer working on Python Workers
Cloudflare
Episode: #568: Cloudflare Python Workers
Dominik Picheta
Cloudflare Workers Runtime team member who helped bring Python to Cloudflare Workers
Cloudflare
Episode: #568: Cloudflare Python Workers
Jeff Triplett
Python developer and Django community member
Django
Episode: #567: Personal AI Agents for Pythonistas
Calvin Hendryx-Parker
CTO and co-founder of a Python consulting agency with decades of Python experience.
Six Feet Up
Episode: #566: State of the art in Python 2026
Pat Decker
DevOps practitioner at Hibu with experience in infrastructure and Python scripting.
Hibu
Episode: #566: State of the art in Python 2026
Reuven Lerner
Python, Pandas and Git trainer who has taught developers for 15 years.
Episode: #566: State of the art in Python 2026
Sydney Runkle
Product manager for open source at LangChain and former Pydantic Core maintainer.
LangChain
Episode: #566: State of the art in Python 2026
Pablo Galindo Salgado
CPython core developer and steering council member
CPython Core Development, Bloomberg (past)
Episode: #565: Tachyon, Python 3.15's Built-in Sampling Profiler

Host

Michael Kennedy
Host of Talk Python To Me; long-time Python developer and entrepreneur

Reviews

4.8 out of 5 stars from 1.2k ratings
  • It helps me to make my own wood đŸȘ” counter for free

    I am a beaver and love free wood counter so I don’t borrow Tim’s as he charges me a 1% wood fee “so expensive” wood expert Jim beaver says

    Apple Podcasts
    5
    BOB (brown, old beaver)đŸŠ«
    Australia2 months ago
  • Great to hear from experts

    I love how Michael gets different experts on the show to share their expertise. In a world where I don’t always trust what Google AI overview is telling me it’s fantastic to hear from real humans.

    Apple Podcasts
    5
    Adam_____7
    Australia3 months ago
  • Love the show hate the intro

    I love the show and the content. The new intro, however, makes me want to throw my phone out the window every time I hear it. It literally makes me want to stop listening to the podcast episode.

    Apple Podcasts
    4
    Agandgold
    United Statesa year ago
  • Eh

    Dropped this podcast after the Temporal episode, which seemed to be mostly complaining about Twitter and people who self-host, rather than pay for the guest’s employer’s managed service. More informative talks, less poorly disguised sales pitches couched in a lot of strange bitterness, please.

    Apple Podcasts
    2
    Thank T.
    United Statesa year ago
  • leftist/democrat morons

    He has no problem with Twitter and all fascist commie democrats’ activist tech political censorship, lying, election interference, etc, but Twitter bought by Elon Musk, OH NO! Absolute dishonesty and delusion to claim you like mastodon for open ness, when all of you were fine with fascist/commie democrat twitter and all tech bias. Very transparent. Very dumb.

    Apple Podcasts
    1
    MnReview
    United States2 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Great mix of guests from security to tooling.
High-quality production and thoughtful topics.
Listener-friendly explanations make complex topics accessible.
Consistently valuable for staying up-to-date in Python ecosystem.
Excellent interviews with deep Python expertise.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#167
United States/Technology
Apple Podcasts
#156
United Kingdom/Technology
Apple Podcasts
#214
Canada/Technology
Apple Podcasts
#127
Italy/Technology
Apple Podcasts
#209
Australia/Technology
Apple Podcasts
#50
Saudi Arabia/Technology

Talking Points

Recent interactions between the hosts and their guests.

#568: Cloudflare Python Workers
Q: Let's maybe round out this conversation by the types of apps that you see people building in Cloudflare Workers in general, and specifically also in Python. Everyone knows what an API that talks to a database looks like, but can I do data science work here?
Hood says Workers are well suited to business logic and IO-bound applications but have limited compute and memory for intensive data science. Small workloads using packages such as Pandas and Parquet can work, while streaming data is preferable to loading large dataframes into memory.
#568: Cloudflare Python Workers
Q: What's the situation or the state with Pyodide Python on WebAssembly in terms of being officially supported by the core developers of Python?
Hood says Emscripten is a Tier 3-supported platform in CPython, meaning it runs in CI on a best-effort basis. He describes a proposal intended to make useful Emscripten Python binaries possible by addressing missing input/output capabilities.
#567: Personal AI Agents for Pythonistas
Q: How do you run it and how do you talk to it?
Triplett explains that the desktop app provides a straightforward chat interface, while users can also run the server themselves and connect to it remotely, including through Tailscale and messaging apps.
#567: Personal AI Agents for Pythonistas
Q: What's your experience with it?
Triplett describes using Hermes for recurring family briefings, weather and schedule checks, lawn-care planning, and reminders, explaining that its persistent operation and memory make it useful for ongoing tasks.
#566: State of the art in Python 2026
Q: What type checker do you use?
The panel mentions MyPy, Ty and Pyrefly. Several speakers favor faster newer checkers, while others say the tools used in their work are influenced by what language models commonly generate.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Gender Skew
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Frequently Asked Questions About Talk Python To Me

What is Talk Python To Me about and what kind of topics does it cover?

A tech-focused podcast that dives deep into Python tooling, ecosystems, and real-world engineering practices. Episodes frequently center on open-source projects, security, AI-assisted development, cloud infrastructure, and software architecture, with guests ranging from maintainers and founders to researchers and practitioners. Listeners are likely software engineers, data scientists, and tech leads who want concrete takeaways, best practices, and context from practitioners actively shaping the Python and broader developer landscape. A notable strength is the steady stream of high-signal guests who are hands-on contributors to widely used tools and frameworks, offering practical insights applicable to day-to-day work and strategic tech deci... more

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Which podcasts are similar to Talk Python To Me?

These podcasts share a similar audience with Talk Python To Me:

1. Python Bytes
2. The Real Python Podcast
3. Software Engineering Radio - the podcast for professional software developers
4. Software Engineering Daily
5. The Stack Overflow Podcast

How many episodes of Talk Python To Me are there?

Talk Python To Me launched 12 years ago and published 567 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Talk Python To Me?

Recent guests on Talk Python To Me include:

1. Hood Chatham
2. Gyeongjae Choi
3. Dominik Picheta
4. Jeff Triplett
5. Calvin Hendryx-Parker
6. Pat Decker
7. Reuven Lerner
8. Sydney Runkle

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