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Artwork for Organic Chemistry

Organic Chemistry - Video

J. Michael McBride

(CHEM 125) This is the first semester in a two-semester introductory course focused on current theories of structure and mechanism in organic chemistry, their historical development, and their basis in experimental observation. The course is open to freshmen with excellent preparation in chemistry and physics, and it aims to develop both taste for original science and intellectual skills necessary... more

PublishesDailyEpisodes37Founded15 years ago
Category
Science

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Artwork for Organic Chemistry

Latest Episodes

After discussing the statistical basis of the law of mass action, the lecture turns to developing a framework for understanding reaction rates. A potential energy surface that associates energy with polyatomic geometry can be realized physically for ... more

After discussing the classic determination of the heat of atomization of graphite by Chupka and Inghram, the values of bond dissociation energies, and the utility of average bond energies, the lecture focuses on understanding equilibrium and rate pro... more

Although molecular mechanics is imperfect, it is useful for discussing molecular structure and energy in terms of standard covalent bonds. Analysis of the Cambridge Structural Database shows that predicting bond distances to within 1% required detail... more

Professor Barry Sharpless of Scripps describes the Nobel-prizewinning development of titanium-based catalysts for stereoselective oxidation, the mechanism of their reactions, and their use in preparing esomeprazole. Conformational energy of cyclic al... more

Understanding conformational relationships makes it easy to draw idealized chair structures for cyclohexane and to visualize axial-equatorial interconversion. After quantitative consideration of the conformational energies of ethane, propane, and but... more

Why ethane has a rotational barrier is still debatable. Analyzing conformational and configurational stereotopicity relationships among constitutionally equivalent groups reveals a subtle discrimination in enzyme reactions. When Baeyer suggested stra... more

After mentioning some legal implications of chirality, the discussion of configuration concludes using esomeprazole as an example of three general methods for producing single enantiomers. Conformational isomerism is more subtle because isomers diffe... more

The chemical mode of action of omeprazole is expected to be insensitive to its stereochemistry, making clinical trials of the proposed virtues of a chiral switch crucial. Design of the clinical trials is discussed in the context of marketing. Otolary... more

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Reviews

3.9 out of 5 stars from 271 ratings
  • Very good

    Very good series

    Apple Podcasts
    5
    glittery koala
    United Kingdom5 years ago
  • Can’t see a thing

    The quality on this video is very low. You are not able to make out a single chart and rarely a word, rendering this useless as a learning tool. That said as an O-Chem course it’s pretty standard, maybe a bit simpler than most judging by the lectures. Nothing new, just lucky-rich Yale students getting silver spoon-fed and easy A’s. Self education… “but look now you can become a genius for free on the internet!”...hahaha… what a joke. Now get back to your wage slave you subservient taxable burden... more

    Apple Podcasts
    1
    Peakabloo
    United States11 years ago
  • Not the professor!

    The professor is great but they did a terrible job editing and from a digital lecture stand point. The entire lecture is filmed from a single camera and they film the professor and the screen at the same time, so you can't make out what the screen says.

    Apple Podcasts
    2
    DrBarr
    United States12 years ago
  • Замечательные лекции

    Замечательный лектор. Постоянно напоминает об ограниченности и применимости химических правил. К каждой теме приводит интересные исторические факты связанные с ее исследованием. Жаль, что качество видео оставляет желать лучшего.

    Apple Podcasts
    5
    cp&me
    Russia13 years ago
  • McBride is a legend

    I don't know how he makes these awesome lectures.

    Apple Podcasts
    5
    Puzzlesperson
    United States14 years ago
  • MacBride hat's einfach drauf

    Super erklärt, mit gutem Vorwissen auch schon vor dem Studium (sehr) gut verständlich! Erklärt dank der theoretischen Tiefe augenöffnende Zusammenhänge. Einziger Kritikpunkt: die schlechte Videoqualität. Da können andere besser. Trotzdem 5*

    Apple Podcasts
    5
    Höhlenmensch
    Germany15 years ago
  • Mtro. Félix Alejandro Jiménez de Santiago

    Excelente colección para aprender y enseñar Química Orgánica. Que sigan presentando éste tipo de trabajos. Gracias

    Apple Podcasts
    5
    kin80
    Mexico15 years ago
  • Well prepared!

    Excellent lecturer, builds logically, with historic insight

    Bravo

    Apple Podcasts
    5
    Tmrome
    Canada15 years ago
  • Прикольная штука!)

    Красочное и четкое видео.) Сразу стал умнее.=)))

    Apple Podcasts
    5
    Dantist138
    Russia15 years ago

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