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Artwork for The Lancet in conversation with

The Lancet in conversation with

The Lancet Group
M-Pox
Renove Trial
WHO
Subclade 1B
Ultra-Processed Foods
Venous Thromboembolism
Democratic Republic Of Congo
Vaccines
Public Health
Direct Oral Anticoagulants
Pulmonary Embolism
Bleeding Risks
Extended Anticoagulation Treatment
Low Back Pain
Sexual Transmission
Public Health Emergency
Follicular Lymphoma
London Global Cancer Week
Nutrition Policy
Chronic Diseases

Jessamy Bagenal, Chloe Wilson, and Callum Davidson—editors at The Lancet—and Gavin Cleaver, The Lancet Group’s Audio Producer, in conversation with the journal’s authors, explore their latest research and its impact on people’s health, healthcare, and health policy. A monthly audio companion to the journal, this podcast covers topics that advance the field of medical research, from exploring treat... more

PublishesMonthlyEpisodes664Founded6 years ago
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Artwork for The Lancet in conversation with

Latest Episodes

What are mRNA vaccine, how do they work, and how might they be used for in the future? And why is there a gap between the evidence and some people’s perception of their safety and efficacy?

Niall Boyce from The Lancet talks to Anna Blakney, biomedic... more

What are cardiometabolic long-term conditions? To mark the publication of a new Lancet Series, editors Niall Boyce and Flávia Geraldes talk to Professor Kamlesh Khunti of the University of Leicester. They learn about a new way of conceptualising comm... more

In this episode of The Lancet In Conversation With, editors Niall Boyce and Bea Gómez Pérez-Nievas are joined by three leading researchers to discuss highlights from The Lancet's special issue on neurology. The conversation covers three landmark stud... more

Do we need to rethink our response to conflict and forced displacement? A new Lancet Commission radically rethinks policy, funding, and practical approaches to humanitarian crises. Chair Professor Paul Spiegel joins Niall Boyce from the Lancet to dis... more

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Recent Guests

Kamlesh Khunti
Professor, University of Leicester
University of Leicester
Episode: What are cardiometabolic long-term conditions?
Tania Nikolcheva
Physician scientist and drug developer; leads clinical development of Presinezumab
Presinezumab development program
Episode: Tania Nikolcheva, Gavin Giovannoni and Tharick Pascoal on the Special issue in Neurology
Gavin Giovannoni
Neurologist specializing in multiple sclerosis
Queen Mary University of London / Royal London Hospital
Episode: Tania Nikolcheva, Gavin Giovannoni and Tharick Pascoal on the Special issue in Neurology
Tharick Pascoal
Behavioral neurologist; Alzheimer's biomarker researcher
University of Pittsburgh
Episode: Tania Nikolcheva, Gavin Giovannoni and Tharick Pascoal on the Special issue in Neurology
Paul Spiegel
Professor, Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Center for Humanitarian Health
Episode: Paul Spiegel: rethinking the humanitarian response to conflict and forced displacement
Anders Fink-Jensen
Professor, University of Copenhagen
University of Copenhagen
Episode: Can semaglutide be used to treat alcohol use disorder?
Louise Chappell
Academic and breast cancer survivor.
Episode: Louise Chappell and Na’ama Carlin on Personal Cancer Stories
Na'ama Carlin
Sociologist, academic, and breast cancer survivor.
Episode: Louise Chappell and Na’ama Carlin on Personal Cancer Stories
Carlos Monteiro
Professor at the University of Sao Paulo, pivotal in defining ultra-processed foods
University of Sao Paulo
Episode: Carlos Monteiro, Camila Corvalán, and Phil Baker on Ultra-Processed Foods and Human Health

Hosts

Niall Boyce
Host and senior Lancet editor, with involvement across Lancet Group programming.
Jonathan Pimm
Senior medical editor contributing to clinical and research discussions.
Ben Abbott
Host of In Conversation with The Lancet and related Lancet podcast content.

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Talking Points

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What are cardiometabolic long-term conditions?
Q: How should we communicate this concept to the general public and patients?
Communications should frame risk without doom, emphasize actionable steps, and highlight that integrated care and prevention can improve overall health, not just individual diseases.
What are cardiometabolic long-term conditions?
Q: What are the implications of the newer therapies for management of these conditions?
GLP-1 receptor agonists and SGLT2 inhibitors have shown robust evidence across diabetes, kidney disease, heart disease, and more, potentially preventing new conditions when used in the right patient with a holistic plan.
What are cardiometabolic long-term conditions?
Q: Why does it help to think about health in this way for patients and health systems?
Because patients often see multiple specialists in silos, which can lead to conflicting advice; holistic care can streamline treatments, reduce patient burden, and leverage therapies that work across several conditions.
What are cardiometabolic long-term conditions?
Q: Kamlesh, welcome to the podcast. Can you describe what cardiometabolic multiple long-term conditions mean in practice?
They are multiple conditions occurring together, requiring a holistic view rather than seeing each in isolation; the approach is to manage them as a whole, since many treatments like blood pressure and lipid management apply across conditions.
Can semaglutide be used to treat alcohol use disorder?
Q: Could you talk us through what you did and what you found in the trial?
We conducted a randomized controlled trial in Copenhagen with adults who had alcohol use disorder and obesity, comparing weekly semaglutide to placebo over six months. The semaglutide group showed a substantial drop in heavy drinking days from 17 to about 5 per 30 days, while the placebo group dropped to about 9, indicating roughly a 50% greater reduction with the drug.

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Frequently Asked Questions About The Lancet in conversation with

What is The Lancet in conversation with about and what kind of topics does it cover?

This program features in-depth conversations with leading researchers, clinicians, and health policy experts about cutting-edge medical research and its real-world impact. Across episodes, guests unpack recent trial results, biomarker advances, and innovative therapies, while also addressing implementation challenges, health equity, and global health priorities. The discussions tend to bridge laboratory findings and clinical practice, often highlighting how new evidence could shift treatment paradigms, improve patient outcomes, and influence policy and healthcare delivery. A notable strength is the blend of rigorous scientific insight with practical considerations for real-world care, including access, cost, and implementation in diverse se... more

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These podcasts share a similar audience with The Lancet in conversation with:

1. The Lancet Voice
2. JAMA Editors' Summary
3. JAMA Medical News
4. NEJM This Week
5. Medicine and Science from The BMJ

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The Lancet in conversation with launched 6 years ago and published 664 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on The Lancet in conversation with?

Recent guests on The Lancet in conversation with include:

1. Kamlesh Khunti
2. Tania Nikolcheva
3. Gavin Giovannoni
4. Tharick Pascoal
5. Paul Spiegel
6. Anders Fink-Jensen
7. Louise Chappell
8. Na'ama Carlin

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