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Genetics in Your World

Genetics Society of America
Drosophila
Fourth Chromosome Resource Project
Human Biology
Genetics and Genomics
Down Syndrome
Insulin Signaling
TGF Beta Signaling
SMAD Proteins
Genetics Society Of America
Cancer
Drosophila Melanogaster
Cancer Genetics
DNA Repair
Longevity Associated Loci
Diversity Outbred Mice
Inbreeding Depression
Cancer Evolution
Evolutionary Biology
Genetics
Dicentric Chromosome Breakage

The Genetics in Your World podcast spotlights noteworthy studies published in GSA Journals GENETICS and G3: Genes|Genomes|Genetics. Through conversations with the authors, you’ll hear about their research and its significance for the fields of genetics and genomics. The podcast is produced by the GSA Early Career Scientist Multimedia Subcommittee.

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PublishesMonthlyEpisodes25Founded5 years ago
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Latest Episodes

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member X has a conversation with Denise Ferkey of University at Buffalo about how natural variation in C. elegans responds to odors. Using hundreds of wild ... more

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee co-chair Anindya Ganguly and member Racheal Asaolu interview Colin LaMont of University of Oslo. They discuss LaMont's work which presents a new mathematica... more

In this episode of Genetics in Your World, GSA Early Career Scientists Multimedia Subcommittee member Racheal Asaolu has a conversation with Dr. Randall J. Roper of the School of Science at Indiana University. They discuss Roper's work. Read his pape... more

In this episode of Genetics in Your World, GSA Early Career Scientists Multimedia Subcommittee member Luke Arnce interviews Caitlin Peaslee of the Center for Embryonic Cell and Gene Therapy at Oregon Health and Science University about her research. ... more

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Recent Guests

Denise Ferkey
Corresponding author of the G3 paper on natural variation in C. elegans olfactory avoidance
University at Buffalo
Episode: Natural Variation in C. elegans 1-octanol Olfactory Avoidance Behavior—A Conversation with Denise Ferkey
Colin LaMont
Postdoctoral researcher working at the Institute of Clinical Medicine and the Institute for Cancer Research, University of Oslo
University of Oslo
Episode: Can We Reconstruct Evolution's Hidden History?—A Conversation with Colin LaMont
Dr. Randall J. Roper
Professor of Genetics, Indiana University
Indiana University
Episode: Curiosity and Compassion in Genetics—A Conversation with Dr. Randall J. Roper
Caitlin Peaslee
PhD candidate at Oregon Health and Science University, Conrad Lab
Oregon Health & Science University
Episode: Mapping Whole-organism Genetic Comorbidities Across Model Species Using Unified Ontologies—A Conversation with Caitlin Peaslee
Srishti Patil
Doctoral student discussing the paper on evolutionary rescue in cancer
German Cancer Research Center
Episode: Bridging Disciplines: How a Theory Meant to Aid in Saving Plant and Animal Species is Helping Scientists Reconsider an Evolutionary Approach to Cancer Treatment — A Conversation with Srishti Patil and Dr. Robert Noble
Rob Noble
Author of the study and mathematician focusing on cancer evolution
City, University of London
Episode: Bridging Disciplines: How a Theory Meant to Aid in Saving Plant and Animal Species is Helping Scientists Reconsider an Evolutionary Approach to Cancer Treatment — A Conversation with Srishti Patil and Dr. Robert Noble
Matt Rockman
Professor of Biology, NYU; study author
New York University
Episode: The Evolutionary Price of Family Ties in Caenorhabditis — A Conversation with Dr. Matt Rockman
Shraddha Lall
Advanced doctoral student in Organismic and Evolutionary Biology
Harvard University
Episode: Variation Reconsidered: Selection Schemes for Phenotypic Variability Beyond Trait Means — A Conversation with Dr. Shraddha Lall
Dr. George Chung
Postdoctoral research scientist focusing on genetic and evolutionary mechanisms of embryonic development
New York University
Episode: Breaking New Ground in Telomeric Repeat Discovery – A Conversation with Dr. George Chung

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Natural Variation in C. elegans 1-octanol Olfactory Avoidance Behavior—A Conversation with Denise Ferkey
Q: What are the broader implications of this work for biology and human health?
Understanding natural genetic variation in sensory perception can inform how genetics influences disease risk and drug responses, and the approach of using wild strains may reframe our understanding of model organisms and translational relevance to human biology.
Natural Variation in C. elegans 1-octanol Olfactory Avoidance Behavior—A Conversation with Denise Ferkey
Q: How does GWAS help connect genetic variation to olfactory behavior in this context?
GWAS scans genomes of many wild strains to identify variants whose presence correlates with differences in olfactory avoidance behavior, enabling researchers to map phenotype differences to specific genomic regions and potentially to particular receptors or signaling pathways.
The Evolutionary Price of Family Ties in Caenorhabditis — A Conversation with Dr. Matt Rockman
Q: Could you please explain the meaning of inbreeding depression?
Inbreeding depression is the decline in an individual's fitness, including survival and reproductive success, as relatedness between its parents increases, largely due to recessive deleterious variants becoming homozygous.
Can We Reconstruct Evolution's Hidden History?—A Conversation with Colin LaMont
Q: What are the future directions for this framework?
LaMont suggests extending the theory to more complex fitness landscapes, incorporating epistasis, and applying the method to cancer data and other rich datasets to see broader scientific impact beyond the initial algorithmic contribution.
Can We Reconstruct Evolution's Hidden History?—A Conversation with Colin LaMont
Q: How does ancestral bias help in inferring selection without reconstructing full histories?
The framework shows that you can infer selection by focusing on the value function and the lineage dynamics of alleles, rather than requiring complete reconstruction of allele frequencies over time, which is often unobserved.

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Frequently Asked Questions About Genetics in Your World

What is Genetics in Your World about and what kind of topics does it cover?

This show focuses on cutting-edge genetics and genomics research, presenting deep dives into recent studies published in GENETICS and G3: Genes|Genomes|Genetics. Episodes feature conversations with the researchers themselves, unpacking study aims, methods, findings, and practical implications for clinical translation, population genetics, and bioinformatics. A standout pattern is the blend of theory with real-world applications—ranging from evolutionary dynamics and cancer evolution to infertility and developmental genetics—often framed through approachable narratives, expert anecdotes, and thoughtful discussion about future directions and data-driven tools. Listeners are likely researchers, clinicians, and graduate students who want to und... more

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Genetics in Your World launched 5 years ago and published 25 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Genetics in Your World?

Recent guests on Genetics in Your World include:

1. Denise Ferkey
2. Colin LaMont
3. Dr. Randall J. Roper
4. Caitlin Peaslee
5. Srishti Patil
6. Rob Noble
7. Matt Rockman
8. Shraddha Lall

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