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From Concept to Medicine - A Comprehensive Drug Development Journey

Jim Mitchell
Drug Development
Clinical Trials
Drug Discovery
Biopharmaceutical Classification System
Personalized Medicine
FDA
Drug Pricing
Maximum Absorbable Dose
Pharmacokinetics
Drug Manufacturing
Safety
Bioavailability
ADME
Medicinal Chemistry
Research Funding
Formulation
Efficacy
In Vitro-In Vivo Correlation
In Vitro, In Vivo Correlation
Pharmacology

Welcome to a Complete Drug Development Journey!

Have you ever wondered how groundbreaking medicines go from a scientist’s vision to life-saving treatments in hospitals and pharmacies worldwide? The journey of drug development is an intricate, high-stakes adventure—filled with scientific breakthroughs, regulatory twists, and the relentless pursuit of innovation.

In this podcast, we take you behind ... more

PublishesDailyEpisodes270Founded6 months ago
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Artwork for From Concept to Medicine

Latest Episodes

Nearly 45% of all deaths from non-communicable diseases worldwide are caused by cardiovascular disease—a staggering reality that frames the story of atorvastatin, better known as Lipitor. In this episode of From Concept to Medicine’s Periodic Table o... more

In this compelling Deep Dive, we explore the unglamorous but absolutely essential world of medical device documentation. From design inception to post-market surveillance, documentation isn't just red tape—it's the backbone of compliance, traceabilit... more

In this expansive episode of The Deep Dive, we explore the full lifecycle of liraglutide, a first-generation GLP-1 receptor agonist that helped redefine how we treat both type 2 diabetes and obesity. From the early 20th-century discovery of incretin ... more

In this compelling episode of The Deep Dive, we explore the multifaceted story of pioglitazone, a thiazolidinedione (TZD) insulin sensitizer used to treat type 2 diabetes. From its origins in 1980s Japan to its development as a follow-up to troglitaz... more

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Recent Guests

Expert Guest
An expert in CMC processes
Episode: 37 - CMC Considerations in Preclinical Stage (S3E7)

Hosts

Host 1
Host providing insights and facilitating discussions throughout the drug development journey.
Speaker 1
One of the key speakers discussing critical topics in drug development.
Speaker 2
A co-host providing multiple perspectives on the pharmaceutical landscape.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Talking Points

Recent interactions between the hosts and their guests.

185 - Episode 5 - Good Documentation Practices (GDP) in Medical Devices - The ALCOA+ Standard (S25E5)
Q: How does this translate to the digital world?
The ALCOA+ principles are absolutely the foundation for electronic records, requiring secure systems that prevent unauthorized access and ensuring data integrity through robust validation practices.
185 - Episode 5 - Good Documentation Practices (GDP) in Medical Devices - The ALCOA+ Standard (S25E5)
Q: What's the main framework, the big rules governing medical device quality, at least here in the US?
The big one we're talking about is FDA 21 CFR Part 820, which lays out the current good manufacturing practice requirements for every medical device maker in the US.
180 - Season 12 Recap & Closing the Journey (S12E15)
Q: What innovations do you think will really shape the next decade in drug development?
AI and machine learning will become more integrated, leading to truly personalized medicine and improved predictive models for human responses.
Naproxen (S24E4)
Q: What about acetaminophen, like Tylenol? That's another big one.
Acetaminophen is not an NSAID and works in a different way, primarily for pain and fever, but not for inflammation.
40 - Handling Deviations and Non-Conformances (S19E2)
Q: From everything we've discussed today, what do you think is the most crucial element of effectively handling deviations?
Conducting a thorough and accurate root cause analysis.

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Frequently Asked Questions About From Concept to Medicine

What is From Concept to Medicine about and what kind of topics does it cover?

The content explores the multi-faceted journey of drug development, illuminating the stages from innovative concepts in drug discovery to regulatory approval and market commercialization. Common subjects include the scientific and regulatory challenges faced during preclinical testing and clinical trials, as well as the strategic considerations that pharmaceutical companies must navigate to ensure successful market access and patient safety. Each episode is characterized by in-depth analyses, expert interviews, and case studies, making it a valuable resource for professionals in the pharmaceutical industry and those interested in the intricacies of drug development. The series stands out for its commitment to educating listeners about not j... more

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1. Chemistry For Your Life
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5. The History of Chemistry

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From Concept to Medicine launched 6 months ago and published 270 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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