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Artwork for Beyond the Endpoint
Clinical Research
Autism
Diabetes
Obesity
Glp-1 Agonists
Hypertension
Clinical Trials
Cardiovascular Health
Cancer Trials
Cardiovascular Disease
Healthcare Access
Salt Consumption
Wearable Technologies
Patient Advocacy
Protein
Federal Funding For Research
Glp-1
FDA
Duke Clinical Research Institute
Grief

The Duke Clinical Research Institute is drawing on gold-standard research and real-world evidence to bring you Beyond the Endpoint, a podcast that is demystifying clinical research and healthcare through conversations with renowned clinicians and scientists.

PublishesTwice monthlyEpisodes45Founded9 years ago
Number of ListenersCategory
Science

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Artwork for Beyond the Endpoint

Latest Episodes

During a cardiac event, every minute without CPR reduces survival chances by 10%. In this episode, DCRI's Tyler Cope discusses a coordinated effort to train nearly 20,000 people across North Carolina in a single day and what it takes to get more byst... more

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Nearly 40% of Americans have experienced back pain in the past three months, yet treatment hasn't kept pace with the science. Host Emily O'Brien talks with DCRI researcher Steven George about biopsychosocial models of care, pragmatic trials, and buil... more

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Double-board-certified pediatrician and allergist/immunologist Zach Rubin joins Manesh Patel for an evidence-based discussion on allergy science. The conversation dives into the differences between allergies and sensitivities, recent shifts in food a... more

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Guests Michael Pencina and Suresh Balu join the Beyond the Endpoint hosts to explore the impact of AI in healthcare. They discuss the role of AI-powered tools in research, clinical care, and operations, while examining evidence standards, transparenc... more

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Recent Guests

Steven George
DCRI researcher focusing on biopsychosocial models for prevention and treatment of chronic musculoskeletal pain
Duke Clinical Research Institute
Episode: From Research to Relief: Raising the Standard in Back Pain Treatment
Dr. Zachary Rubin
Double board certified pediatrician specializing in allergy and immunology
Oakbrook Allergists
Episode: All About Allergies: The Evolution of Care & Evidence with Dr. Zach Rubin
Dr. Michael Pencina
Former Vice Dean for Data Science, Chief AI Scientist at United Health Group
United Health Group
Episode: From Innovation to Implementation: AI in Action
Suresh Balu
Associate Dean for Innovation and Partnership, Program Director of the Duke Institute for Health Innovation
Duke Institute for Health Innovation
Episode: From Innovation to Implementation: AI in Action
Dr. Jennifer Green
Board-certified endocrinologist and professor of medicine at Duke University
Duke University, DCRI
Episode: Connecting the Dots: The Broader Applications of GLP-1s and Where We’re Headed Next
Dr. Neha Pagidipati
Cardiologist and faculty member at DCRI
Duke Clinical Research Institute
Episode: Obesity, GLP-1s, and the Evidence: What the Data Tells Us
Jennifer Norris
A physician assistant at the Duke Center for metabolic and weight loss surgery, working closely with patients considering weight loss surgery.
Duke Center for Metabolic and Weight Loss Surgery
Episode: It's Not Just the Scale: Supporting Sustainable Change in Obesity Treatment
Dr. Lauren Franz
Board-certified child and adolescent psychiatrist with extensive experience in autism research
Duke Center for Autism and Brain Development
Episode: Understanding Autism: Insights from Research and Practice
Dr. Adrian Hernandez
Executive Director of the Duke Clinical Research Institute, Vice Dean, Professor, and practicing cardiologist.
Duke Clinical Research Institute
Episode: Playing to Advance Care: A Championship Mindset in Clinical Research

Hosts

Dr. Manesh Patel
Chief of the Division of Cardiology and Clinical Pharmacology, head of cardiology at Duke Medicine, and faculty member at the Duke Clinical Research Institute, Dr. Manesh Patel engages in various discussions related to cardiovascular health and clinical research methodologies.
Dr. Emily O'Brien
Population health researcher, faculty member at the Duke Department of Population Health Sciences, and co-host, Dr. Emily O'Brien focuses on public health issues and innovative healthcare solutions in her discussions.

Chart Rankings

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Apple Podcasts
#185
Saudi Arabia/Science

Talking Points

Recent interactions between the hosts and their guests.

All About Allergies: The Evolution of Care & Evidence with Dr. Zach Rubin
Q: What are current developments in allergy medicine?
FDA has approved a needle-free option for anaphylaxis management and a sublingual strip for administering epinephrine is being developed, which could simplify treatment.
All About Allergies: The Evolution of Care & Evidence with Dr. Zach Rubin
Q: How do you describe the basic biology and immunology behind an allergy?
Allergy is an abnormal immune response to foreign substances, and the immune system has broader roles beyond just infection protection, including recognition of self versus non-self.
Stepping Up: From Curiosity to Confidence — What to Know Before You Join a Trial
Q: What are some reasons that people might hesitate to participate in research?
Reasons include concern over receiving the same level of care and apprehension about being a 'guinea pig' without understanding their risks and benefits.
Stepping Up: From Curiosity to Confidence — What to Know Before You Join a Trial
Q: How do you respond to participants who may be hesitant about the science behind the study?
The research studies undergo a large vetting process, including reviews by ethics committees before reaching participants.
Bridging Science and Policy: A Conversation with Dr. Robert Califf
Q: What do you think the biggest challenges are of us getting things that work to our patients?
Dr. Califf explains the unique issues faced in the U.S. healthcare system, emphasizing its financialization and the disparity in access to quality care.

Audience Metrics

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Listeners per Episode
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Location
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Frequently Asked Questions About Beyond the Endpoint

What is Beyond the Endpoint about and what kind of topics does it cover?

Focused on unraveling the complexities of clinical research and healthcare, the content features in-depth discussions with leading experts in various medical fields. Significant emphasis is placed on topics such as cardiovascular health, obesity treatment, diabetes management, and the evolving landscape of clinical trials. Additionally, the conversations explore the impact of recent scientific advancements, innovative therapies, and the importance of equitable healthcare access. Unique to this show is its blend of clinical insights interwoven with personal stories from healthcare professionals and patients, making it both informative and relatable for listeners interested in medical science and patient advocacy.

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Which podcasts are similar to Beyond the Endpoint?

These podcasts share a similar audience with Beyond the Endpoint:

1. The Daily

How many episodes of Beyond the Endpoint are there?

Beyond the Endpoint launched 9 years ago and published 45 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

How do I contact Beyond the Endpoint?

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What guests have appeared on Beyond the Endpoint?

Recent guests on Beyond the Endpoint include:

1. Steven George
2. Dr. Zachary Rubin
3. Dr. Michael Pencina
4. Suresh Balu
5. Dr. Jennifer Green
6. Dr. Neha Pagidipati
7. Jennifer Norris
8. Dr. Lauren Franz

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