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Between Two COO's with Michael Koenig

Michael Koenig
Artificial Intelligence
Home2go
EU Artificial Intelligence Act
SPAC
Procurement
Executive Recruitment
Mozilla
Capitalism
Identity and Access Management
Spreedly
Noda
Cowboy Space
Give First
AI Capex
Moburst
Fellow
Saas
Vendor Negotiations
C-Suite Roles
GDPR

Between Two COOs is hosted by veteran COO Michael Koenig and brings together Chief Operating Officers, executives, and business leaders to share real insights on operations, leadership, scaling, AI, and execution. Featuring COOs from companies like LVMH, Vodafone, Automattic, Lime, JumpCloud, Grafana Labs, and Cotopaxi, plus top VCs like Brad Feld and Seth Levine. Whether you're a COO, VP of Ops, ... more

PublishesWeeklyEpisodes70Founded5 years ago
Number of ListenersCategories
ManagementBusinessEntrepreneurship

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Artwork for Between Two COO's

Latest Episodes

Tom Masterson, COO of Deep Genomics, on AI drug discovery where precision beats creativity. He explains how the company's siRNA model picked an approved cholesterol drug out of 3,500 candidates for a target it had never seen, why it designs toxic mol... more

Paul Kedrosky of SK Ventures says AI capex is driving up to 70 percent of US GDP growth, and most of it is now borrowed. He walks through the money map, the 2029 maturity wall, why AI tokens are a deflationary commodity, and three ways the AI bubble ... more

Lior Eldan, co-founder and COO of Moburst, has reinvented what his agency sells three times, from app store optimization to AI products. He explains why replacing people with AI is backwards, why managers have to do the work, and why automating a bro... more

Part 2 of 2. Part 1 is here: betweentwocoos.com/65

In part 1, Joe Yaffe explained how an orbital data center works. This time, the question is

whether it works as a business.

In this episode, Joe and Michael discuss:

• Why Cowboy Space ... more

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Recent Guests

Tom Masterson
Chief Operating Officer at Deep Genomics
Deep Genomics
Episode: Tom Masterson, Deep Genomics COO on AI Drug Discovery That Learned the Rules
Paul Kedrosky
MIT fellow, advisor to major asset managers, CNBC contributor and co-host of The Dick and Paul Show
SK Ventures
Episode: The AI Bubble Has a Due Date. It's 2029 | Paul Kedrosky, SK Ventures
Lior Eldan
COO and Co-Founder of Moburst
Moburst
Episode: Lior Eldan, Moburst COO on Reinventing the Marketing Agency Before AI Eats It
Joe Yaffe
COO and Chief Legal Officer at Cowboy Space
Cowboy Space
Episode: Joe Yaffe, COO at Cowboy Space, on Whether Data Centers in Space Are Cheaper
Riikka Söderlund
Chief Operating Officer at Katana Cloud Inventory
Katana Cloud Inventory
Episode: Riikka Söderlund, Katana COO, on Why AI Won't Know Your Product Exists
Wade Foster
Co-founder and CEO of Zapier
Zapier
Episode: Zapier CEO Wade Foster on Why AI Is a People Problem, Not a Tech Problem
Zulema Quintans
COO of Noda
Noda
Episode: Zulema Quintans, COO of Noda, on Why Your OKRs Don't Get Done
Peter Rojas
Founder of Gizmodo and Engadget; operator, investor, and executive at Mozilla
Mozilla
Episode: Peter Rojas, New Products at Mozilla, on Why Ideas Don't Decide Success
Greg Keller
Co-founder and Chief Technology Officer of JumpCloud
JumpCloud
Episode: AI Agents Need Logins Too: Identity, Security, and the Future of AI | Greg Keller, CTO, JumpCloud

Host

Michael Koenig
Host of Between Two COOs with Michael Koenig

Reviews

5.0 out of 5 stars from 13 ratings
  • Operations is so easy

    Hearing Michael interview other COOs will give you the impression that the job is mostly for those serendipitous types who are as comfortable accepting responsibility for accidental success as they are nonchalant about climbing Mount Everest.

    Ok you caught me, I’m a friend of Micheal (at least until he reads this review) so I’m biased. But I listen because as an entrepreneur the stories and lessons have helped me steer my own business better than I could have done by ignoring them.

    Michael, wh... more

    Apple Podcasts
    5
    skeltoac
    United States4 years ago
  • New COO

    Thanks for taking the time to produce such a high quality podcast. As a new COO I’ve already taken away some gems from your conversations. I look forward to all the upcoming episodes.

    Apple Podcasts
    5
    Meg In Chicago
    United States5 years ago
  • New Favorite Podcast

    Best resource out there for COOs! My new FAVORITE podcast.

    Apple Podcasts
    5
    alf2125
    United States5 years ago
  • Between 2 COO’s

    Very interesting and informative discussion about being a COO by two COOs. Worth the time spent listening. Very relatable.

    Apple Podcasts
    5
    urol doc
    United States5 years ago

Listeners Say

Key themes from listener reviews, highlighting what works and what could be improved about the show.

Guests consistently deliver practical, battle-tested ops guidance.
High-quality discussions with senior operators and founders.
The format with COOs as hosts creates highly relatable content for listeners.
Listeners gain usable frameworks for scaling and leadership.

Chart Rankings

How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.

Apple Podcasts
#118
Norway/Business/Management
Apple Podcasts
#206
Israel/Business/Management

Talking Points

Recent interactions between the hosts and their guests.

Tom Masterson, Deep Genomics COO on AI Drug Discovery That Learned the Rules
Q: How did Tom Masterson end up at Deep Genomics and what is his role now?
Tom describes moving from sales and operations in medical devices to broad business leadership, eventually joining Deep Genomics to handle business development, strategy, and operations, and rising to Chief Operating Officer to align R&D with the business and board needs.
Tom Masterson, Deep Genomics COO on AI Drug Discovery That Learned the Rules
Q: What does Deep Genomics actually do?
The company merges AI with biology to build a biological foundation model and training application models that predict drug discovery outcomes, aiming to streamline and potentially transform how drugs are identified and developed.
Riikka Söderlund, Katana COO, on Why AI Won't Know Your Product Exists
Q: What is the six-week sprint approach and why does it work for Katana?
Six-week sprints provide a structured cadence that balances fast iteration with meaningful impact, allowing teams to test initiatives, learn quickly, and adjust execution without waiting for quarterly cycles.
Riikka Söderlund, Katana COO, on Why AI Won't Know Your Product Exists
Q: How does Katana stay relevant as AI changes how brands reach customers?
By focusing on inventory visibility, extensibility through open APIs, and a marketing-informed COO perspective that ties product storytelling to operations, Katana helps brands surface what is actually in stock and what can be manufactured, rather than relying on generic AI content.
Automattic Chief Quality Officer, Lance Willett, on What It Takes to Power 45% of the Web and Learning from a $250K Mistake
Q: How does Automattic manage culture and tooling at such scale, and what lessons have been learned about standardization vs. autonomy?
The company moved from autonomy to more standardized tools and processes to gain efficiency, reduce vendor sprawl, and improve knowledge transfer. The approach includes a single source of truth via centralized tools (GitHub, Figma, Linear), governance around AI experiments, and open communication to spread best practices across teams.

Audience Metrics

Listeners, social reach, demographics and more for this podcast.

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Frequently Asked Questions About Between Two COO's

What is Between Two COO's about and what kind of topics does it cover?

This show concentrates on operations, leadership, and execution at scale, with frequent deep dives into how COOs and senior operators drive process, strategy, and AI adoption across diverse industries. Guests range from climate-tech and space-enabled compute ventures to payments, identity, and enterprise SaaS, offering practical frameworks, governance practices, and lessons learned from building durable, growth-focused organizations. A standout throughline is the emphasis on sustainable operating systems, cross-functional collaboration, and the human side of leadership in fast-moving tech environments, making it valuable for current and aspiring operators looking for actionable, battle-tested insights.

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1. The Dick & Paul Show
2. The Julia La Roche Show
3. The Peter Zeihan Podcast Series
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5. Better Offline

How many episodes of Between Two COO's are there?

Between Two COO's launched 5 years ago and published 70 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Between Two COO's?

Recent guests on Between Two COO's include:

1. Tom Masterson
2. Paul Kedrosky
3. Lior Eldan
4. Joe Yaffe
5. Riikka Söderlund
6. Wade Foster
7. Zulema Quintans
8. Peter Rojas

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